29634-62-6

Basic information

• Product Name: 1,2-Propanedione, 3-bromo-1-phenyl-
• CAS NO: 29634-62-6
• Molecular Formula: C9H7BrO2
• Molecular Weight: 227.057
• Mol File: 29634-62-6.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: 1,2-Propanedione, 3-bromo-1-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Propanedione, 3-bromo-1-phenyl-(29634-62-6)
• EPA Substance Registry System: 1,2-Propanedione, 3-bromo-1-phenyl-(29634-62-6)

Safety Data

• Hazardous Substances Data: 29634-62-6(Hazardous Substances Data)

Usage

Chemical Structure

1,2-Propanedione, 3-bromo-1-phenyl-

Explanation

This structure consists of a propanedione (diketone) backbone with a bromine atom at the 3-position and a phenyl group attached to the 1-position.

Explanation

The bromine atom and phenyl group are substituents that can be used for further chemical reactions, while the dione (diketone) group is a functional group that provides reactivity and versatility in organic synthesis.

Explanation

Due to its unique structure and functional groups, 1,2-Propanedione, 3-bromo-1-phenylis used as a reagent in the synthesis of various organic compounds and pharmaceutical drugs.

Explanation

The compound's structure and functional groups make it a valuable building block for creating a wide range of chemical structures, which can be used in the development of pharmaceutical drugs and other organic compounds.

Explanation

The presence of a bromine atom and a phenyl group in the molecule allows for a wide range of chemical reactions and modifications, making it a versatile building block in organic chemistry.

Explanation

The specific properties and potential applications of 1,2-Propanedione, 3-bromo-1-phenylmake it an important compound in the fields of organic chemistry and pharmaceutical development, as it can be used to create new and innovative chemical structures.

Functional Groups

Bromine atom, Phenyl group, and Dione (diketone)

Application

Reagent in organic synthesis and pharmaceutical research

Potential Use

Production of pharmaceutical drugs and other organic compounds

Versatility

Building block for various chemical structures

Importance

Component in organic chemistry and pharmaceutical development

Upstream product

• 579-07-7 1-Phenylpropane-1,2-dione 
• 85616-23-5 2-ethoxy-1-phenyl-2-propen-1-one 
• 93-55-0 1-phenyl-propan-1-one 
• 103-79-7 1-phenyl-acetone 

Downstream Products

• 90808-01-8 (5-Methoxy-7,8-dihydro-6H-cyclopenta[e]imidazo[1,2-a]pyrimidin-2-yl)-phenyl-methanone 
• 90808-03-0 (5-Methylsulfanyl-7,8-dihydro-6H-cyclopenta[e]imidazo[1,2-a]pyrimidin-2-yl)-phenyl-methanone 
• 170449-25-9 2-Bromomethyl-6,7-dimethyl-3-phenyl-quinoxaline 
• 73161-52-1 [2-(4-fluoro-benzylamino)-thiazol-5-yl]-phenyl-ethanedione 
• 73161-53-2 (2-anilino-thiazol-5-yl)-phenyl-ethanedione 
• 128979-10-2 phenyl(thiazol-4-yl)methanone 
• 1167623-55-3 phenyl[6-(1-trityl-1H-imidazol-4-yl)imidazo[1,2-a]pyridin-2-yl]methanone 
• 1421922-39-5 [2-(2,5-dimethyl-4-nitrobenzyl)-1,3-thiazol-4-yl](phenyl)methanone hydrobromide 
• 3574-02-5 2-phenylnaphtho[1,2-d]oxazole 
• 1305264-02-1 C₁₇H₁₁N₃O₂ 
• 1305263-60-8 C₁₇H₁₄N₄O 

Relevant articles and documents

Synthesis of 4-(3-oxo-3-phenylpropyl)morpholin-4-ium chloride analogues and their inhibitory activities of nitric oxide production in lipopolysaccharide-induced BV2 cells

Based on our previous report that 3-morpholino-1-phenylpropan-1-one 2, one of the fluoxetine's simplified morpholino analogue, inhibited nitric oxide (NO) production, in this paper, various substituted benzene analogues with morpholine hydrochloride of 2 were synthesized and their inhibitory effects on NO production in lipopolysaccharide (LPS)-induced BV2 cells were tested. Among the synthesized compounds, 2-trifluoromethyl analogue 16n (IC50 = 8.6 μM) showed a significantly higher inhibitory activity than that of the parent compound 2a (IC50 > 50 μM) and suppressed NO production dose-dependently without cytotoxicity. Compound 16n also inhibited iNOS expression in LPS-induced BV2 cells at 2, 10 and 20 μM concentrations. These results suggest that compound 16n inhibited NO production by suppressing the expression of iNOS and can be used as a lead structure for developing new inhibitor of NO production.

SUBSTITUTED AMINOTHIAZOLES AS INHIBITORS OF NUCLEASES

The invention provides compounds represented by the structural formula (1): wherein R1, R2, R3, R4, R5, R6 are as defined in the claims. The compounds are inhibitors of nucleases, and are useful in particular in a method of treatment and/or prevention of proliferative diseases, neurodegenerative diseases, and other genomic instability associated diseases.

FUSED TRICYCLIC COMPOUNDS WITH ADENOSINE A2a RECEPTOR ANTAGONIST ACTIVITY

The present invention relates to certain certain fused tricyclic heteroaryl rings compounds of the Formula (I) (also referred to herein as the "Fused Tricyclic Compounds"), wherein M, Q, U, W, X, Y, Z, R1, R2, and R3, and rings C and D are as herein described. The present invention also provides compositions comprising at least one Fused Tricyclic Compound, and use of such compounds in the treatment of central nervous system diseases or disorders such as Parkinson's disease.