29713-96-0

Basic information

• Product Name: N,O-bis[(benzyloxy)carbonyl]tyrosine
• Synonyms: N,O-Bis[(benzyloxy)carbonyl]tyrosine; tyrosine, N,O-bis[(phenylmethoxy)carbonyl]-
• CAS NO: 29713-96-0
• Molecular Formula: C₂₅H₂₃NO₇
• Molecular Weight: 449.4526
• Mol File: 29713-96-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 669°C at 760 mmHg
• Flash Point: 358.4°C
• Density: 1.304g/cm³
• Vapor Pressure: 8.26E-19mmHg at 25°C
• Refractive Index: 1.605
• CAS DataBase Reference: N,O-bis[(benzyloxy)carbonyl]tyrosine(CAS DataBase Reference)
• NIST Chemistry Reference: N,O-bis[(benzyloxy)carbonyl]tyrosine(29713-96-0)
• EPA Substance Registry System: N,O-bis[(benzyloxy)carbonyl]tyrosine(29713-96-0)

Safety Data

• Hazardous Substances Data: 29713-96-0(Hazardous Substances Data)

Upstream product

• 60-18-4 L-tyrosine 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 5254-68-2 N-(N,O-bis-benzyloxycarbonyl-L-tyrosyl)-L-isoleucine methyl ester 
• 83549-85-3 1-(N,O-bis-benzyloxycarbonyl-L-tyrosyl)-L-proline-methyl ester 
• 64693-63-6 N,O-bis-benzyloxycarbonyl-L-tyrosyl chloride 
• 16789-90-5 N-(N,O-bis-benzyloxycarbonyl-L-tyrosyl)-L-tyrosine ethyl ester 
• 121177-11-5 N,O-bis-benzyloxycarbonyl-L-tyrosyl=>L-tyrosyl=>L-tyrosine ethyl ester 
• 51783-65-4 (S)-4-(4-benzyloxycarbonyloxy-benzyl)-oxazolidine-2,5-dione 
• 122389-68-8 N,O-bis-benzyloxycarbonyl-L-tyrosine cyanomethyl ester 
• 7641-11-4 -leucinmethylester 
• 15364-47-3 N,O-Dibenzyloxycarbonyl-Tyr-Ser-methylester 
• 57228-47-4 O,N-(Dicarbobenzoxy)-L-tyrosyl-aethylamid 
• 57228-38-3 N-Carbobenzoxy-L-tyrosyl-di-n-propylamid 
• 22840-22-8 N,O-Bis-benzyloxycarbonyl-Tyr-(N,N-dimethyl-hydrazid) 
• 57228-50-9 N,O-bis-benzyloxycarbonyl-L-tyrosine benzylamide 
• 100350-48-9 Z-Tyr(Z)-Gly-N₂H₂Boc 

Relevant articles and documents

Deprotection of t-butyl esters of amino acid derivatives by nitric acid in dichloromethane

The extension of the deprotection procedure of t-butylated carboxyl function using HNO3 in CH2Cl2 to a number of appropriately selected N-Z- derivatives of natural amino acid esters was investigated. The method was found to work effectively with alanine, phenylalanine, serine and the dipeptide aspartame, but the reagent brought about a number of unwanted transformations with tyrosine, methionine and tryptophan. Suitable protection of functions present in the latter ones allowed selective ester dealkylation, but tyrosine underwent unavoidable fast preliminary ring nitration. 2000 Elsevier Science Ltd.

O-Tertiary amino-alkyl-N-benzoyl tyrosil amides

Tyrosine derivatives of the formula: STR1 wherein: R1 is a linear or branched-chain alkyl group having 1-6 carbon atoms, terminating by a tertiary amino group; R 2 is an unsubstituted, monosubstituted or di-substituted phenyl or benzyloxy group, the substituent being --Cl, --Br, --NO2, --OCH3, --CH3 or --CF3 ; R3 is a primary, secondary or tertiary amino group or an aryl-alkylamino group having 7-9 carbon atoms; and salts of said tyrosine derivatives with pharmaceutically acceptable acids.