297131-85-2Relevant articles and documents
Methodology based on chiral silanes in the synthesis of polypropionate-derived natural products - Total synthesis of epothilone A
Zhu, Bin,Panek, James S.
, p. 1701 - 1714 (2007/10/03)
Epothilones A and B (1 and 2) are natural products with potent antitumor activity. These compounds have a Taxol-like mechanism of action against tumor cells. A total synthesis of epothilone A (1) is reported, which is based on the synthesis and union of t