2972-85-2

Basic information

• Product Name: [1-(4-methoxyphenyl)ethylidene]propanedinitrile
• Synonyms: 2-(1-(4-Methoxyphenyl)ethylidene)malononitrile
• CAS NO: 2972-85-2
• Molecular Formula: C₁₂H₁₀N₂O
• Molecular Weight: 198.2206
• Mol File: 2972-85-2.mol
• Article Data: 18

Chemical Properties

• Boiling Point: 342.8°C at 760 mmHg
• Flash Point: 140.4°C
• Density: 1.117g/cm³
• Vapor Pressure: 7.36E-05mmHg at 25°C
• Refractive Index: 1.548
• CAS DataBase Reference: [1-(4-methoxyphenyl)ethylidene]propanedinitrile(CAS DataBase Reference)
• NIST Chemistry Reference: [1-(4-methoxyphenyl)ethylidene]propanedinitrile(2972-85-2)
• EPA Substance Registry System: [1-(4-methoxyphenyl)ethylidene]propanedinitrile(2972-85-2)

Safety Data

• Hazardous Substances Data: 2972-85-2(Hazardous Substances Data)

Usage

Description

[1-(4-methoxyphenyl)ethylidene]propanedinitrile, a chemical compound with the molecular formula C12H11N3O, is a nitrile derivative featuring a benzene ring with a methoxy group and a carboxylic acid group attached to an ethylidene chain. [1-(4-methoxyphenyl)ethylidene]propanedinitrile is recognized for its potential pharmacological activities and is often utilized in organic synthesis and pharmaceutical research.

Uses

Used in Pharmaceutical Research:
[1-(4-methoxyphenyl)ethylidene]propanedinitrile is used as a research compound for its potential antitumor properties, making it a valuable asset in cancer research. Its unique structure and pharmacological activities contribute to the development of novel therapeutic strategies against various types of cancer.
Used in Organic Synthesis:
As an intermediate, [1-(4-methoxyphenyl)ethylidene]propanedinitrile is employed in the synthesis of various other compounds, showcasing its versatility and importance in the field of organic chemistry. Its ability to be modified and incorporated into different molecular structures highlights its utility in creating new and potentially beneficial chemical entities.
Used in Chemical Intermediates Industry:
[1-(4-methoxyphenyl)ethylidene]propanedinitrile is used as a key intermediate in the production of various pharmaceuticals and other chemical products. Its role in this industry is crucial, as it enables the creation of a wide range of compounds with diverse applications, from medical treatments to industrial processes.

Upstream product

• 18394-32-6 (1-Chlorethyliden)propandinitril 
• 100-66-3 methoxybenzene 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 109-77-3 malononitrile 

Downstream Products

• 10432-50-5 3-(4-Methoxy-phenyl)-3-methyl-cyclopropane-1,1,2,2-tetracarbonitrile 
• 128342-40-5 6-(furan-2-yl)-4-(4-methoxyphenyl)-2-thioxo-1,2-dihydropyridine-3-carbonitrile 
• 128342-41-6 4-(4-methoxyphenyl)-6-(thiophen-2-yl)-2-thioxo-1,2-dihydropyridine-3-carbonitrile 
• 89507-36-8 [6-Amino-5-cyano-4-(4-methoxy-phenyl)-thiopyran-(2E)-ylidene]-cyano-acetic acid ethyl ester 
• 79111-73-2 4-(4-Methoxyphenyl)-2-methylthio-penta-1,4-dien-1,1,5,5-tetracarbonitril 
• 79111-75-4 (E)-2,6,6-Tricyano-5-(4-methoxy-phenyl)-3-methylsulfanyl-hexa-2,5-dienoic acid ethyl ester 
• 78564-17-7 3-cyano-4-(4-methoxyphenyl)-6-phenylpyridine-2(1H)-thione 
• 128342-38-1 3-cyano-4-(4-methoxyphenyl)-6-(4-methylphenyl)-pyridin-2(1H)-thione 
• 128342-37-0 6-(4-Chloro-phenyl)-4-(4-methoxy-phenyl)-2-thioxo-1,2-dihydro-pyridine-3-carbonitrile 
• 128342-39-2 4,6-Bis-(4-methoxy-phenyl)-2-thioxo-1,2-dihydro-pyridine-3-carbonitrile 
• 84488-33-5 2-{1-(4-Methoxy-phenyl)-2-[5-(4-methoxy-phenyl)-[1,2]dithiol-(3Z)-ylidene]-ethylidene}-malononitrile 
• 84488-34-6 5-Imino-2,7-bis-(4-methoxy-phenyl)-5H-thieno[3,2-b]thiopyran-6-carbonitrile 
• 86641-63-6 2-{(4-Methoxy-phenyl)-[5-(4-methoxy-phenyl)-3-methylsulfanyl-thiophen-2-yl]-methylene}-malononitrile 
• 89507-33-5 [6-Amino-5-cyano-4-(4-methoxy-phenyl)-thiopyran-(2E)-ylidene]-cyano-acetic acid methyl ester 

Relevant articles and documents

A [5 + 1] annulation strategy for the synthesis of multifunctional biaryls and: P -teraryls from 1,6-Michael acceptor ketene dithioacetals

A new type of ketene dithioacetal, 2-(3,3-bis-methylsulfanyl-1-arylallylidene)malononitriles containing 1,4 and 1,6-Michael acceptors, were synthesized to study their reactivity for the synthesis of a new molecular entity. We report a [5 + 1] annulation s

"on Water" Direct Catalytic Vinylogous Aldol Reaction of Silyl Glyoxylates

The unique reactivity of water in the direct catalytic vinylogous aldol reaction of silyl glyoxylates is reported. With the hydrogen-bonding networks from water, the unfavorable homogeneous reactions in organic solvents were severely suppressed, and the "

Syntheses of donor-acceptor-functionalized dihydroazulenes

The dihydroazulene (DHA)/vinylheptafulvene (VHF) photo/thermoswitch has been of interest for use in molecular electronics and advanced materials. The switching between the two isomers has previously been found to depend strongly on the presence of donor a