297773-47-8

Basic information

• Product Name: 3-AMINO-3-(5-BROMOPYRIDIN-3-YL)PROPIONIC ACID
• Synonyms: 3-AMINO-3-(5-BROMOPYRIDIN-3-YL)PROPIONIC ACID
• CAS NO: 297773-47-8
• Molecular Weight: 0
• Mol File: 297773-47-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 3-AMINO-3-(5-BROMOPYRIDIN-3-YL)PROPIONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-AMINO-3-(5-BROMOPYRIDIN-3-YL)PROPIONIC ACID(297773-47-8)
• EPA Substance Registry System: 3-AMINO-3-(5-BROMOPYRIDIN-3-YL)PROPIONIC ACID(297773-47-8)

Safety Data

• Hazardous Substances Data: 297773-47-8(Hazardous Substances Data)

Upstream product

• 113118-81-3 5-bromopyridine-3-carbaldehyde 
• 141-82-2 malonic acid 

Downstream Products

• 1423134-22-8 (3S)-3-[5-(4-fluoro-3-nitrophenyl)pyridin-3-yl]-3-[({(3R)-1-[3-(piperidin-4-yl)propanoyl]piperidin-3-yl}carbonyl)amino]propanoic acid 
• 1423135-11-8 3-{[(3R)-1-(3-{1-[(tert-butoxy)carbonyl]piperidin-4-yl}propanoyl)piperidin-3-yl]formamido}-3-[5-(4-fluoro-3-nitrophenyl)pyridin-3-yl]propanoic acid 
• 1423135-10-7 tert-butyl 4-{3-[(3R)-3-({1-[5-(4-fluoro-3-nitrophenyl)pyridin-3-yl]-3-methoxy-3-oxopropyl}carbamoyl)piperidin-1-yl]-3-oxopropyl}piperidine-1-carboxylate 
• 1423134-21-7 (3S)-3-[5-(4-cyano-3-fluorophenyl)pyridin-3-yl]-3-[({(3R)-1-[3-(piperidin-4-yl)propanoyl]piperidin-3-yl}carbonyl)amino]propanoic acid 
• 1423135-09-4 3-({[(3R)-1-{3-[1-(tert-butoxycarbonyl)piperidin-4-yl]propan oyl}piperidin-3-yl]carbonyl}amino)-3-[5-(4-cyano-3-fluorophenyl)pyridin-3-yl]propanoic acid 
• 1423135-06-1 tert-butyl 4-{3-[(3R)-3-({1-[5-(4-cyano-3-fluorophenyl)pyridin-3-yl]-3-methoxy-3-oxopropyl}carbamoyl)piperidin-1-yl]-3-oxopropyl}piperidine-1-carboxylate 
• 1423134-20-6 (3S)-3-[5-(3-cyano-4-fluorophenyl)pyridin-3-yl]-3-[({(3R)-1-[3-(piperidin-4-yl)propanoyl]piperidin-3-yl}carbonyl)amino]propanoic acid 
• 1423135-03-8 3-({[(3R)-1-{3-[1-(tert-butoxycarbonyl)piperidin-4-yl]propanoyl}piperidin-3-yl]carbonyl}amino)-3-[5-(3-cyano-4-fluorophenyl)pyridin-3-yl]propanoic acid 
• 1423135-00-5 tert-butyl 4-{3-[(3R)-3-({1-[5-(3-cyano-4-fluorophenyl)pyridin-3-yl]-3-methoxy-3-oxopropyl}carbamoyl)piperidin-1-yl]-3-oxopropyl}piperidine-1-carboxylate 
• 1423134-97-7 3-({[(3R)-1-{3-[1-(tert-butoxycarbonyl)piperidin-4-yl]propanoyl}piperidin-3-yl]carbonyl}amino)-3-{5-[2-(2-fluoroethoxy)phenyl]pyridin-3-yl}propanoic acid 
• 1423134-94-4 tert-butyl 4-(3-{(3R)-3-[(1-{5-[2-(2-fluoroethoxy)phenyl]pyridin-3-yl}-3-methoxy-3-oxopropyl)carbamoyl]piperidin-1-yl}-3-oxopropyl)piperidine-1-carboxylate 
• 1423134-93-3 tert-butyl 4-{3-[(3R)-3-({1-[5-(2-hydroxyphenyl)pyridin-3-yl]-3-methoxy-3-oxopropyl}carbamoyl)piperidin-1-yl]-3-oxopropyl}piperidine-1-carboxylate 
• 1423134-19-3 (3S)-3-{5-[2-(2-fluoroethoxy)phenyl]pyridin-3-yl}-3-[({(3R)-1-[3-(piperidin-4-yl)propanoyl]piperidin-3-yl}carbonyl)amino]propanoic acid 
• 1423134-18-2 (3S)-3-{5-[4-(2-fluoroethoxy)phenyl]pyridin-3-yl}-3-[({(3R)-1-[3-(piperidin-4-yl)propanoyl]piperidin-3-yl}carbonyl)amino]propanoic acid 

Relevant articles and documents

An expedient method for resolution of 3-amino-3-(3′-pyridyl)propionic acid and related compounds

Preparation of methyl (S)-3-amino-3-(3′-pyridyl)propionate dihydrochloride in high enantiomeric purity by selective crystallization of a diastereomeric salt of a carboxylic acid precursor (W-BOC-protected) with (1R,2S)-(-)-ephedrine is described. Further demonstration of the usefulness of this procedure to resolve other 3-amino-3-[(substituted)pyridyl]propionic acids is also described.

COMPOUNDS FOR BINDING TO THE PLATELET SPECIFIC GLYCOPROTEIN IIB/IIIA AND THEIR USE FOR IMAGING OF THROMBI

The present invention relates to novel fluorine containing compounds, methods for their preparation, the intermediates of the synthesis, their use as diagnostic agents, especially for imaging of thrombi. The invention relates to positron emission tomography (PET) agents and associated precursor reagents, and methods for producing such radiolabeled agents for imaging of thrombi in a mammalian body. More particulariy, the invention relates to small, nonpeptide, high-affinity, specific-binding glycoprotein llb/IIIa antagonists for imaging of thrombi.