29786-38-7

Basic information

• Product Name: 1-(3-Bromophenyl)-cyclobutanecarbonitrile
• Synonyms: 1-(3-BroMophenyl)cyclobutane-1-carbonitrile
• CAS NO: 29786-38-7
• Molecular Formula: C₁₁H₁₀BrN
• Molecular Weight: 236.11
• Mol File: 29786-38-7.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(3-Bromophenyl)-cyclobutanecarbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-Bromophenyl)-cyclobutanecarbonitrile(29786-38-7)
• EPA Substance Registry System: 1-(3-Bromophenyl)-cyclobutanecarbonitrile(29786-38-7)

Safety Data

• Hazardous Substances Data: 29786-38-7(Hazardous Substances Data)

Usage

General Description

1-(3-Bromophenyl)-cyclobutanecarbonitrile is a chemical compound with the molecular formula C11H9BrN. It is a white to light yellow crystal powder that is insoluble in water. 1-(3-Bromophenyl)-cyclobutanecarbonitrile is commonly used in organic synthesis as a building block for the production of various pharmaceutical and agrochemical products. Its cyclobutane ring structure makes it a valuable intermediate in the synthesis of diverse organic compounds. Additionally, the presence of the bromine and nitrile functional groups in its chemical structure enhances its reactivity and makes it a useful starting material for the preparation of more complex chemical compounds.

Upstream product

• 31938-07-5 (3-bromophenyl)acetonitrile 
• 109-64-8 1,3-dibromo-propane 

Downstream Products

• 29786-48-9 1-(3-bromophenyl)cyclobutane-1-carboxamide 
• 29786-59-2 <1-(m-Bromophenyl)-cyclobutyl>-carbonylisocyanat 
• 29770-35-2 (<1-(m-Bromophenyl)-cyclobutyl>-carbonyl)-harnstoff 
• 29786-18-3 (<1-(m-Bromophenyl)cyclobutyl>carbonyl)carbamsaeuremethylester 
• 29786-30-9 (<1-(m-Bromophenyl)cyclobutyl>carbonyl)carbamsaeureethylester 
• 926261-31-6 1-(3-bromophenyl)cyclobutanecarboxylic acid 
• 1195178-54-1 1-(3-bromophenyl)cyclobutanecarbonyl azide 
• 1195172-98-5 1-(1-(3-bromophenyl)cyclobutyl)-3-(4-(2-methylpyridin-4-yl)phenyl)urea 
• 1160498-80-5 (1-(3-(1H-pyrazolo[3,4-b]pyridin-4-yl)phenyl)cyclobutyl)methanamine trifluoroacetate 
• 1160501-51-8 (1-(3-(3-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-4-yl)phenyl)cyclobutyl)methanamine 
• 1160499-05-7 C₁₇H₁₄N₄ 

Relevant articles and documents

Synthesis method of arylcyclobutane compound

The present invention discloses a method for synthesizing an arylcyclobutane compound to 1eq phenylacetonitrile and 1.1eq 1-bromo-3-chloropropane as raw material, N,N- dimethylacetamide as a solvent, plus 2.5eq sodium hydride, under the protection of iner

Identification of A Novel Small-Molecule Binding Site of the Fat Mass and Obesity Associated Protein (FTO)

N-(5-Chloro-2,4-dihydroxyphenyl)-1-phenylcyclobutanecarboxamide (N-CDPCB, 1a) is found to be an inhibitor of the fat mass and obesity associated protein (FTO). The crystal structure of human FTO with 1a reveals a novel binding site for the FTO inhibitor and defines the molecular basis for recognition by FTO of the inhibitor. The identification of the new binding site offers new opportunities for further development of selective and potent inhibitors of FTO, which is expected to provide information concerning novel therapeutic targets for treatment of obesity or obesity-associated diseases.