2979-05-7

Basic information

• Product Name: Cyclohexene, 1,1'-(1,3-butadiyne-1,4-diyl)bis-
• CAS NO: 2979-05-7
• Molecular Formula: C16H18
• Molecular Weight: 210.319
• Mol File: 2979-05-7.mol
• Article Data: 64

Chemical Properties

• CAS DataBase Reference: Cyclohexene, 1,1'-(1,3-butadiyne-1,4-diyl)bis-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexene, 1,1'-(1,3-butadiyne-1,4-diyl)bis-(2979-05-7)
• EPA Substance Registry System: Cyclohexene, 1,1'-(1,3-butadiyne-1,4-diyl)bis-(2979-05-7)

Safety Data

• Hazardous Substances Data: 2979-05-7(Hazardous Substances Data)

Upstream product

• 5768-10-5 1,4-bis(1-hydroxycyclohexyl)buta-1,3-diyne 
• 21983-34-6 1-(bromoethynyl)cyclohex-1-ene 
• 89343-06-6 tris-iso-propylsilyl acetylene 
• 931-49-7 1-ethenylcyclohexene 
• 622-79-7 benzyl azide 
• 172739-50-3 7-hydroxy-2-trifluoromethyl-4H-benzopyran-4-one 
• 5706-85-4 2-hydroxy-1-(4-hydroxyphenyl)ethan-1-one 
• 4039-82-1 Benzyl propargyl ether 
• 536-74-3 phenylacetylene 
• 845266-44-6 1,5-di(cyclohex-1-en-1-yl)penta-1,4-diyn-3-one 
• 110-96-3 diisobutylamine 
• 201230-82-2 carbon monoxide 
• 274-47-5 imidazo[1,5-a]pyridine 
• 118264-44-1 (cyclohex-1-en-1-ylethynyl)magnesium bromide 

Downstream Products

• 93160-16-8 2,5-di(cyclohex-1-enyl)thiophene 

Relevant articles and documents

Cobalt-catalyzed homocoupling of terminal alkynes: Synthesis of 1,3-diynes

Homocoupling of terminal alkynes proceeds using Co2(CO)8 pretreated with phenanthroline to give good yields of 1,3-diynes under mild conditions.

Synthesis of 8-carbo substituted 2-(trifluoromethyl)-4H-furo[2,3-h]chromen-4-ones and their thienoangelicin derivatives

Tandem Sonogashira cross-coupling and heteroannulation of 7-hydroxy-8-iodo-2-(trifluoromethyl)chromen-4-one with terminal acetylenes afforded the 8-carbo–substituted 2-(trifluoromethyl)-4H-furo[2,3-h]chromen-4-ones 2a–i. The latter were reacted with methyl mercaptoacetate in the presence of triethylamine to afford the corresponding 7,8-dihydro-5H-furo[2,3-h]thieno[2,3-c]chromen-5-one derivatives 3a–i. The structures of the prepared compounds were characterized using a combination of NMR (1H-, 13C & 19F-), IR and mass spectroscopic techniques, and confirmed by single X-ray crystal structures of 8-(3-fluorophenyl)-2-(trifluoromethyl)-4H-furo[2,3-h]chromen-4-one (2b) and 2-phenyl-7-(trifluoromethyl)-7,8-dihydro-5H-furo[2,3-h]thieno[2,3-c]chromen-5-one (3a). The highlight of this investigation is the conversion of 2-(trifluoromethyl)–substituted 4H-furo[2,3-h]chromen-4-ones into trifluoromethyl–substituted thienoangelicin analogues.

Copper-Mediated Deacylative Coupling of Ynones via C-C Bond Activation under Mild Conditions

The intermolecular deacylative coupling of unstrained ynones via C-C bond activation was accomplished by a CuCl-bpy system under mild reaction conditions. This protocol features facile cleavage of the C-C bond at room temperature, broad substrate scope, and efficient construction of important symmetric and unsymmetrical 1,3-diyne adducts through homo or cross coupling of ynones, respectively. The preliminary mechanistic investigations indicated that an acyl copper(III) complex is likely involved in this process.

Polymer-Supported Cu–Nanoparticle as an Efficient and Recyclable Catalyst for Oxidative Homocoupling of Terminal Alkynes

Abstract: Copper nanoparticle on polyaniline support was synthesised by using in situ polymerisation and composite formation technique. This metal polymer nanocomposites material is found to be efficient for homocoupling of terminal alkynes which afford s