29816-35-1

Basic information

• Product Name: Ethanedioic acid,1,2-bis[2-(1-phenylethylidene)hydrazide]
• Synonyms: Ethanedioicacid, bis[(1-phenylethylidene)hydrazide] (9CI); Oxalic acid, bis[(a-methylbenzylidene)hydrazide](8CI); NSC 243543
• CAS NO: 29816-35-1
• Molecular Formula: C18H18 N4 O2
• Molecular Weight: 322.367
• Mol File: 29816-35-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Ethanedioic acid,1,2-bis[2-(1-phenylethylidene)hydrazide](CAS DataBase Reference)
• NIST Chemistry Reference: Ethanedioic acid,1,2-bis[2-(1-phenylethylidene)hydrazide](29816-35-1)
• EPA Substance Registry System: Ethanedioic acid,1,2-bis[2-(1-phenylethylidene)hydrazide](29816-35-1)

Safety Data

• Hazardous Substances Data: 29816-35-1(Hazardous Substances Data)

Upstream product

• 56352-60-4 oxalamic acid-(1-phenyl-ethylidenehydrazide) 
• 996-98-5 oxalic acid hydrazide 
• 98-86-2 acetophenone 
• 1122-62-9 2-acetylpyridine 

Downstream Products

• 1222194-67-3 C₁₈H₂₂N₄O₂ 
• 256479-28-4 CH₃C(C₆H₅)NNHC(O)C(O)NHNC(C₆H₅)CH₃Cu(H₂O)2(SO₄) 
• 385819-89-6 bis(acetophenone oxaloyldihydrazone)copper(II) chloride 
• 385819-87-4 bis(acetophenone oxaloyldihydrazone)cobalt(II) chloride 
• 303009-75-8 Zn(acetophenone oxaloyldihydrazone)2Cl₂*H₂O 

Relevant articles and documents

Synthesis, characterization, molecular modeling and antibacterial activity of N1′, N2′-bis[1-(pyridin-2-yl)ethylidene] oxalohydrazide and its metal complexes

New complexes of N1′,N2′-bis[1-(pyridin- 2-yl)ethylidene]oxalohydrazide (H2L) with Cr3+, Mn 2+, Fe3+, Co2+, Ni2+, Cu 2+, Cd2+, VO2+ and Ag+ have been prepared and characterized. The ligand has 10-12 buffering range and pK's of 4.62, 7.78 and 9.45. The IR spectra showed the neutral, (mono- or dibasic) bidentate, tridentate or tetradentate of H2L. The molar conductance values, in DMSO, are in the range of nonelectrolytes. An octahedral geometry is proposed for the Cr3+, Mn2+, Fe3+, Ni 2+; VO2+ complexes and square-planar for the Co 2+ and Cu2+ complexes. The ESR spectra support the mononuclear species for [VO(H2L)SO4-(H2O) 2]·H2O and [Cu(H2L)(OAc) 2]·H2O. The molecular parameters have been calculated to confirm the geometry of the ligand and its complexes. The ligand and some complexes were screened against Bacillus thuringiensis (Bt) as Gram positive and Pseudomonas aeuroginosa (Pa) as Gram negative bacteria using the inhibitory zone diameter. The data showed no effect for the complexes on Pa bacteria growth except [Ag(H2L)(NO3)]H2O which had a high activity. Cu2+, VO2+ and Ag+ complexes exhibit activity against BT; Cu2+complex is the highest one.