298183-97-8

Basic information

• Product Name: (3aS,10Z,14S,16aS)-14-[(2S)-butan-2-yl]-1-(N,N-dimethyl-L-leucyl-L-isoleucyl)-8-methoxy-13,16-dioxo-1,2,3,3a,12,13,14,15,16,16a-decahydro-9,5-(metheno)pyrrolo[3,2-b][1,5,8]oxadiazacyclopentadecine
• Synonyms: pentanamide, 2-(dimethylamino)-4-methyl-N-[(1S,2S)-2-methyl-1-[[(3aS,10Z,14S,16aS)-3,3a,12,13,14,15,16,16a-octahydro-8-methoxy-14-[(1S)-1-methylpropyl]-13,16-dioxo-9,5-metheno-5H-pyrrolo[3,2-b][1,5,8]oxadiazacyclopentadecin-1(2H)-yl]carbonyl]butyl]-, (2S)-
• CAS NO: 298183-97-8
• Molecular Formula: C₃₄H₅₃N₅O₆
• Molecular Weight: 627.8145
• Mol File: 298183-97-8.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 858.363°C at 760 mmHg
• Flash Point: 472.921°C
• Density: 1.094g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.515
• CAS DataBase Reference: (3aS,10Z,14S,16aS)-14-[(2S)-butan-2-yl]-1-(N,N-dimethyl-L-leucyl-L-isoleucyl)-8-methoxy-13,16-dioxo-1,2,3,3a,12,13,14,15,16,16a-decahydro-9,5-(metheno)pyrrolo[3,2-b][1,5,8]oxadiazacyclopentadecine(CAS DataBase Reference)
• NIST Chemistry Reference: (3aS,10Z,14S,16aS)-14-[(2S)-butan-2-yl]-1-(N,N-dimethyl-L-leucyl-L-isoleucyl)-8-methoxy-13,16-dioxo-1,2,3,3a,12,13,14,15,16,16a-decahydro-9,5-(metheno)pyrrolo[3,2-b][1,5,8]oxadiazacyclopentadecine(298183-97-8)
• EPA Substance Registry System: (3aS,10Z,14S,16aS)-14-[(2S)-butan-2-yl]-1-(N,N-dimethyl-L-leucyl-L-isoleucyl)-8-methoxy-13,16-dioxo-1,2,3,3a,12,13,14,15,16,16a-decahydro-9,5-(metheno)pyrrolo[3,2-b][1,5,8]oxadiazacyclopentadecine(298183-97-8)

Safety Data

• Hazardous Substances Data: 298183-97-8(Hazardous Substances Data)

Upstream product

• 37174-12-2 (2S,3S)-2-(dimethylamino)-3-methylpentanoic acid 
• 929896-10-6 (2R,3S)-1-(tert-butoxycarbonyl)-2-(tert-butyldimethylsilyloxy)methyl-3-(3-formyl-4-methoxy-phenoxy)-pyrrolidine 
• 929896-11-7 (2R,3S)-1-(tert-butoxycarbonyl)-2-(tert-butyldimethylsilyloxy)methyl-3-[3-((Z)-2-iodovinyl)-4-methoxy-phenoxy]-pyrrolidine 
• 929896-13-9 (2R,3S)-1-(tert-butoxycarbonyl)-2-hydroxymethyl-3-[3-((Z)-2-iodovinyl)-4-methoxy-phenoxy]-pyrrolidine 
• 929896-14-0 (2R,3S)-1-(tert-butoxycarbonyl)-2-formyl-3-[3-((Z)-2-iodovinyl)-4-methoxy-phenoxy]-pyrrolidine 
• 929896-15-1 (2R,3S)-1-(tert-butoxycarbonyl)-3-[3-((Z)-2-iodovinyl)-4-methoxy-phenoxy]-proline 
• 929896-09-3 (2R,3S)-{1-(tert-butoxycarbonyl)-3-[3-((Z)-2-iodovinyl)-4-methoxy-phenoxy]-prolyl}-isoleucinamide 
• 929896-08-2 C₂₅H₃₅N₃O₆ 
• 929896-12-8 C₂₀H₂₇N₃O₄ 
• 1761-62-2 5-iodosalicyclaldehyde 
• 90-02-8 salicylaldehyde 
• 42298-41-9 5-iodo-2-methoxy-benzaldehyde 
• 216229-02-6 (2R,3S)-1-(tert-butoxycarbonyl)-2-[(tert-butyldimethylsilyloxy)methyl]-3-hydroxypyrrolidine 
• 2439-37-4 (S)-2-dimethylamino-4-methyl-pentanoic acid 

Relevant articles and documents

A general route to cyclopeptide alkaloids: total syntheses and biological evaluation of paliurines e and F, ziziphines N and Q, abyssenine A, mucronine E, and analogues

A full account of the total syntheses of the cyclopeptide alkaloids paliurine E and F, ziziphine N and Q, abyssenine A, and mucronine E is provided. A key feature of the syntheses involves an intramolecular amidation of a vinyl iodide, which allows us sim