298219-06-4

Basic information

• Product Name: 4-(4-chlorophenyl)-5-methyl-N-phenylthiazol-2-amine
• Synonyms: 4-(4-chlorophenyl)-5-methyl-N-phenylthiazol-2-amine
• CAS NO: 298219-06-4
• Molecular Weight: 300.812
• Mol File: 298219-06-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-(4-chlorophenyl)-5-methyl-N-phenylthiazol-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-chlorophenyl)-5-methyl-N-phenylthiazol-2-amine(298219-06-4)
• EPA Substance Registry System: 4-(4-chlorophenyl)-5-methyl-N-phenylthiazol-2-amine(298219-06-4)

Safety Data

• Hazardous Substances Data: 298219-06-4(Hazardous Substances Data)

Upstream product

• 1462328-07-9 4-chloropropiophenone O-acetyloxime 
• 103-72-0 phenyl isothiocyanate 
• 877-37-2 2-bromo-1-(4-chlorophenyl)-1-propanone 
• 333-20-0 potassium thioacyanate 
• 62-53-3 aniline 

Relevant articles and documents

Copper-Catalyzed Coupling of Oxime Acetates with Isothiocyanates: A Strategy for 2-Aminothiazoles

A new strategy for 2-aminothiazoles is developed via the copper-catalyzed coupling of oxime acetates with isothiocyanates. Various 4-substituted and 4,5-disubstituted 2-aminothiazoles were formed smoothly under mild reaction conditions. This process involved copper-catalyzed N-O bond cleavage, activation of vinyl sp2 C-H bonds, and C-S/C-N bond formations. It is noteworthy that the oxime acetates were used not only as a substrate but also as a single oxidant.