29865-50-7

Basic information

• Product Name: 1-(4'-methylphenyl)-2-nitropropane
• Synonyms: 1-(4'-methylphenyl)-2-nitropropane
• CAS NO: 29865-50-7
• Molecular Weight: 179.219
• Mol File: 29865-50-7.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 1-(4'-methylphenyl)-2-nitropropane(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4'-methylphenyl)-2-nitropropane(29865-50-7)
• EPA Substance Registry System: 1-(4'-methylphenyl)-2-nitropropane(29865-50-7)

Safety Data

• Hazardous Substances Data: 29865-50-7(Hazardous Substances Data)

Upstream product

• 104-87-0 4-methyl-benzaldehyde 
• 52287-56-6 (E)-1-methyl-4-(2-nitroprop-1-en-1-yl)benzene 
• 52287-56-6 1-(p-tolyl)-2-nitropropene 
• 79-24-3 Nitroethane 
• 72538-32-0 1-(4-methylbenzyl)-2,4,6-triphenylpyridin-1-ium tetrafluoroborate 

Downstream Products

• 114306-23-9 1-(4-methylphenyl)propan-2-one oxime 
• 2096-86-8 p-Tolylaceton 

Relevant articles and documents

Iridium-catalyzed highly chemoselective and efficient reduction of nitroalkenes to nitroalkanes in water

An iridium-catalyzed highly chemoselective and efficient transfer hydrogenation reduction of structurally diverse nitroalkenes was realized at very low catalyst loading (S/C = up to 10000 or 20?000), using formic acid or sodium formate as a traceless hydride donor in water. Excellent functionality tolerance is also observed. The turnover number and turnover frequency of the catalyst reach as high as 18?600 and 19?200 h-1, respectively. An inert atmosphere protection is not required. The reactivities of nitroalkenes are dependent on their substitution pattern, and the pH value is a key factor to accomplish the complete conversion and excellent chemoselectivity. Purification of products is achieved by simple extraction without column chromatography. The reduction procedure is facilely amplified to 10 g scale at 10?000 S/C ratio. The potential of this green reduction in enantioselective hydrogenation has been demonstrated.

The highly chemoselective transfer hydrogenation of the carbon-carbon double bond of conjugated nitroalkenes by a rhodium complex

Chemoselective transfer hydrogenation of conjugated nitroalkenes catalyzed by [RhCl2Cp·]2-diamine complex (Cp ·=η5-C5Me5) using HCOOH/Et3N (5:2) (TEAF) as a hydrogen source was realized. A variety of nitrostyrenes, β-methyl nitrostyrenes, and 3-methyl-4-nitro-5-alkenyl- isoxazoles were reduced smoothly in good to excellent yields in short reaction time. Other functional groups are inert under the reaction conditions.

The yeast-mediated reduction of nitrostyrenes in organic solvent systems

A range of nitrostyrenes have been reduced with dried baker's yeast in an organic solvent system. It was found that the reduction proceeded smoothly to give the corresponding nitroalkanes in good yield and with higher efficiency than the corresponding aqueous reaction system. No evidence for reduction of the nitro group was observed. In the case of β-methyl nitrostyrenes, racemic mixtures were formed, and it was shown that this is not due to racemization of the product.