299216-13-0

Basic information

• Product Name: 2-Oxazolidinone, 3-amino-4-(phenylmethyl)-, (4S)-
• CAS NO: 299216-13-0
• Molecular Formula: C10H12N2O2
• Molecular Weight: 192.217
• Mol File: 299216-13-0.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: 2-Oxazolidinone, 3-amino-4-(phenylmethyl)-, (4S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Oxazolidinone, 3-amino-4-(phenylmethyl)-, (4S)-(299216-13-0)
• EPA Substance Registry System: 2-Oxazolidinone, 3-amino-4-(phenylmethyl)-, (4S)-(299216-13-0)

Safety Data

• Hazardous Substances Data: 299216-13-0(Hazardous Substances Data)

Upstream product

• 299216-14-1 (4S)-4-benzyl-3-[(E)-propylideneamino]-1,3-oxazolan-2-one 
• 90719-32-7 (S)-4-Benzyl-2-oxazolidinone 
• 299216-19-6 (S)-3-(methoxycarbonylmethylidene)amino-4-phenylmethyl-2-oxazolidinone 
• 299216-18-5 (S)-3-(benzylidene)amino-4-phenylmethyl-2-oxazolidinone 

Downstream Products

• 373363-48-5 (S)-3-(5'-chloro-1'-pentylidene)amino-4-phenylmethyl-2-oxazolidinone 
• 409305-50-6 (S)-3-(p-methylbenzylidene)amino-4-phenylmethyl-1,3-oxazolidin-2-one 
• 409305-51-7 (S)-3-(3'-nitrobenzylidene)amino-4-phenylmethyl-2-oxazolidinone 
• 575465-43-9 (4S)-4-benzyl-3-{[(1R)-1-(1,3-dioxolan-2-yl)propyl]amino}-1,3-oxazolan-2-one 
• 575465-42-8 (4S)-4-benzyl-3-{[(E)-2,2-dimethoxyethylidene]amino}-1,3-oxazolan-2-one 
• 609772-38-5 (S)-4-Benzyl-3-[2-methyl-1-phenyl-prop-(Z)-ylideneamino]-oxazolidin-2-one 
• 409305-54-0 (S)-3-(trans-cinnamylidene)amino-4-phenylmethyl-2-oxazolidinone 
• 409305-61-9 (4S,1'R)-3-(1'-ethyl-3'-butenylamino)-4-phenylmethyl-2-oxazolidinone 

Relevant articles and documents

A simple and efficient approach to the N-amination of oxazolidinones using monochloroamine

Chiral nonracemic N-amino cyclic carbamates (ACCs) are important auxiliaries for certain asymmetric transformations. In the past they have been synthesized from oxazolidinones using methods that require the preparation and use of non-atom economical aminating agents that can be difficult to prepare, and often strong bases. In what follows we describe a mild and operationally simple method for the direct N-amination of oxazolidinones that use NH2Cl derived from commercial bleach.

A novel hydrazide type organocatalyst for enantioselective Diels-Alder reactions

The development of a new class of hydrazide type organocatalyst, (4R,5R)-1,3-bis(isopropylamino)-4,5-dihenylimidazolidin-2-one 2a, for enantioselective Diels-Alder reactions between cyclopentadiene and α,β-unsaturated aldehydes are presented. The new organocatalyst 2a promoted the reaction, affording Diels-Alder adducts in good yields with good levels of enantioselectivity.

Mn-mediated coupling of alkyl iodides and ketimines: A radical addition route to α,α-disubstituted α-aminoesters

(Chemical Equation Presented) Coupling of primary and secondary alkyl iodides with N-acylhydrazonoesters via Mn-mediated photolysis conditions affords access to tert-alkyl amines.