29973-91-9 Usage
Description
4-Benzyloxy-3-methoxyphenylacetic acid is an aromatic phenyl acetic acid derivative that has been synthesized through the benzylation of 4-hydroxy-3-methoxyphenylacetic acid. 4-BENZYLOXY-3-METHOXYPHENYLACETIC ACID is characterized by its aromatic structure and functional groups, which contribute to its potential applications in various fields.
Uses
Used in Pharmaceutical Industry:
4-Benzyloxy-3-methoxyphenylacetic acid is used as a reactant in the synthesis of 1,2-bis(4-benzyloxy-3-methoxyphenyl)-3-hydroxy-propionic acid, which may have potential applications in the development of pharmaceutical compounds. The synthesis of such molecules can lead to the creation of new drugs with specific therapeutic properties, targeting various medical conditions.
Used in Chemical Synthesis:
In the field of organic chemistry, 4-Benzyloxy-3-methoxyphenylacetic acid can be utilized as a building block for the synthesis of more complex molecules. Its unique structure and functional groups make it a valuable component in the creation of novel chemical entities with potential applications in various industries, including pharmaceuticals, agrochemicals, and materials science.
Used in Research and Development:
4-Benzyloxy-3-methoxyphenylacetic acid can also be employed in research and development settings, where it can be used to study the properties and reactivity of aromatic phenyl acetic acid derivatives. This knowledge can be applied to the design and synthesis of new molecules with specific functions and applications, contributing to the advancement of scientific understanding and technological innovation.
Check Digit Verification of cas no
The CAS Registry Mumber 29973-91-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,9,9,7 and 3 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 29973-91:
(7*2)+(6*9)+(5*9)+(4*7)+(3*3)+(2*9)+(1*1)=169
169 % 10 = 9
So 29973-91-9 is a valid CAS Registry Number.
InChI:InChI=1/C16H16O4/c1-19-15-9-13(10-16(17)18)7-8-14(15)20-11-12-5-3-2-4-6-12/h2-9H,10-11H2,1H3,(H,17,18)
29973-91-9Relevant articles and documents
Ginos,Brown
, p. 155 (1978)
Preparation method for ivabradine impurities
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Paragraph 0056; 0071; 0073, (2018/09/11)
The invention discloses a preparation method for ivabradine impurities. According to the preparation method, 3-hydroxy-4-methoxyphenylacetic acid (as shown in a formula 1a) and 4-hydroxy-3-methoxyphenylacetic acid (as shown in a formula 1b) are respectively used as a starting raw material and subjected to multiple steps of reactions to prepare two impurities of ivabradine. The preparation method of the invention is simple and realizes high-purity preparation; and the prepared impurities can be used for qualitative and quantitative analysis so as to improve the medication safety of ivabradine.
Functional reversal of (?)-Stepholidine analogues by replacement of benzazepine substructure using the ring-expansion strategy
Li, Wei,Zhang, Li,Xu, Lili,Yuan, Congmin,Du, Peng,Chen, Jiaojiao,Zhen, Xuechu,Fu, Wei
, p. 599 - 607 (2016/10/06)
(?)-Stepholidine is an active ingredient of the Chinese herb Stephania and naturally occurring tetrahydroprotoberberine alkaloid with mixed dopamine receptor D1 agonistic and dopamine receptor D2 antagonistic activities. In this work, a series of novel hexahydrobenzo[4,5]azepino [2,1-a]isoquinolines were designed and synthesized as ring-expanded analogues of (?)-Stepholidine. Initial pharmacological assays demonstrated that a benzazepine replacement was associated with significant increase in selectivity and functional reversal at dopamine receptor D1. Compound-(?)-15e (Ki?=?5.32?±?0.01?nm) is more potent than (?)-Stepholidine (Ki?=?13?nm) and was identified as a selective dopamine receptor D1 antagonist (IC50?=?0.14?μm). Moreover, molecular modeling suggested that (?)-15e might exert its dopamine receptor D1 antagonistic activities through interacting with the transmembrane helix 7 of dopamine receptor D1.
