30011-74-6Relevant articles and documents
Directed Functionalization of Cyano-Substituted Furans and Thiophenes with TMPMgCl·LiCl
Dos Santos, Fernanda M.,Batista, Jo?o H. C.,Vessecchi, Ricardo,Clososki, Giuliano C.
, p. 2795 - 2800 (2015)
A number of novel difunctionalized furans and thiophenes has been prepared by the reaction of the cyano-substituted substrates with TMPMgCl·LiCl followed by the reaction with electrophiles. The crucial metalation step takes place under mild conditions allowing the isolation of desired derivatives in reasonable to good yields.
