30034-49-2

Basic information

• Product Name: 3-Methoxy-4-(benzyloxy)-benzenepropanoic acid
• Synonyms: 3-Methoxy-4-(benzyloxy)-benzenepropanoic acid
• CAS NO: 30034-49-2
• Molecular Formula: C₁₇H₁₈O₄
• Molecular Weight: 286.32242
• Mol File: 30034-49-2.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Methoxy-4-(benzyloxy)-benzenepropanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Methoxy-4-(benzyloxy)-benzenepropanoic acid(30034-49-2)
• EPA Substance Registry System: 3-Methoxy-4-(benzyloxy)-benzenepropanoic acid(30034-49-2)

Safety Data

• Hazardous Substances Data: 30034-49-2(Hazardous Substances Data)

Usage

General Description

3-Methoxy-4-(benzyloxy)-benzenepropanoic acid is a chemical compound with the molecular formula C17H18O4. It is an aromatic compound with a benzene ring and a propionic acid group attached. The presence of a methoxy group and a benzyloxy group on the benzene ring makes it an ortho-substituted compound. 3-Methoxy-4-(benzyloxy)-benzenepropanoic acid is often used as a building block in organic synthesis and medicinal chemistry, and it has potential pharmaceutical applications due to its structural features and properties. The presence of both methoxy and benzyloxy groups makes it a versatile compound for further derivatization and modification, thus offering a wide range of potential applications in pharmaceutical research and drug development.

Upstream product

• 65004-77-5 3-(4-benzyloxy-3-methoxy-phenyl)-propionitrile 
• 77795-22-3 4-benzyloxy-3-methoxycinnamic acid 
• 1135-23-5 3-(4-hydroxy-3-methoxyphenyl)propionic acid 
• 100-44-7 benzyl chloride 
• 116185-11-6 benzyl 3-[4-(benzyloxy)-3-methoxyphenyl]propanoate 
• 186895-24-9 ethyl 3-(4-(benzyloxy)-3-methoxy)propanoate 
• 1135-24-6 (E)-3-(4-hydroxy-3-methoxyphenyl)acrylic acid 
• 61292-90-8 ethyl 3-(4-hydroxy-3-methoxyphenyl)propanoate 
• 1135-24-6 3-(4-hydroxy-3-methoxyphenyl)acrylic acid 
• 28028-62-8 ethyl ferulate 

Downstream Products

• 1135-23-5 3-(4-hydroxy-3-methoxyphenyl)propionic acid 
• 116185-12-7 2,3-bis<<3-methoxy-4-(phenylmethoxy)phenyl>methyl>-butanedioic acid 
• 105245-81-6 3-(4-benzyloxy-3-methoxyphenyl)propionic acid chloride 
• 64974-48-7 N-(4-Benzyloxy-3-methoxymethoxyphenethyl)-4-benzyloxy-3-methoxy-phenylpropionamid 
• 536976-78-0 (2R,4R)-4-[3-(4-Benzyloxy-3-methoxy-phenyl)-propionyloxy]-2-(3-bromo-1-methoxycarbonyl-propyl)-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 67566-04-5 7-methoxy-1-oxaspiro<5.4>deca-6,9-diene-2,8-dione 
• 127399-66-0 1,2,3,4-tetrahydro-7-(benzyloxy)-6-methoxy-2(1H)-naphthalenone 
• 653579-83-0 4-(4-benzyloxy-3-methoxyphenyl)-1-diazobutan-2-one 
• 653579-68-1 7-benzyloxy-2-bromo-6-methoxy-1-naphthaldehyde 
• 653579-65-8 7-benzyloxy-2-bromo-3,4-dihydro-6-methoxy-1-naphthaldehyde 
• 653579-77-2 3-benzyloxy-11,12-dihydro-2-methoxy-8,9-methylenedioxybenzo[i]phenanthridine 
• 653579-75-0 7-benzyloxy-6-methoxy-2-(4,5-methylenedioxy-2-nitrophenyl)-1-naphthaldehyde 
• 653579-71-6 7-benzyloxy-3,4-dihydro-6-methoxy-2-(4,5-methylenedioxy-2-nitrophenyl)-1-naphthaldehyde 
• 69172-20-9 3-(3-methoxy-4-benzyloxyphenyl)propionaldehyde 

Relevant articles and documents

The total syntheses of JBIR-94 and two synthetic analogs and their cytotoxicities against A549 (CCL-185) human small lung cancer cells

We here disclose the total syntheses of the natural polyphenol JBIR-94 and two nonnatural analogs, whose structures are of interest for their bioactivity potential as radical scavengers. Although we initially attempted this by dually acylating both of putrecine's amine nitrogens in a single pot, our endeavors with this method (which has been successfully reported by other groups) proved ineffectual. We accordingly opted for the lengthier approach of acylating each amine individually, which gratuitously prevailed and also aligns with separate literature precedent. Moreover, we here share our analysis of these target compounds’ cytotoxicities and IC50 values against A549 (CCL-185) human small lung cancer cells.

Asymmetric synthesis of O-methylneferine

Diastereoselective Pictet-Spengler reaction of 2-arylethylamine bearing an N-(R)-1-(1-naphthyl)ethylcarbamoyl group with arylacetaldehyde gave 1-benzyltetrahydroisoquinoline in good yield with moderate diastereoselectivity. The reaction was applied to asymmetric synthesis of O-methyl derivative of neferine, an alkaloid of the lotus embryo, Nelumbo nucifera Gaertner.

AMIDES AND METHOD FOR PLANT DISEASE CONTROL WITH THE SAME

N-(α-cyanobenzyl)amide compounds represented by the formula (1): wherein R1 represents a hydrogen atom; a halogen atom; a C1-C6 alkyl group optionally substituted with a halogen atom or the like; or the like, R2 represents a hydrogen atom, a halogen atom, a C1-C6 alkyl group or the like, R3 represents a hydrogen atom or the like, R4 represents a C1-C4 alkyl group, a C3-C4 alkenyl group or the like, R5 represents a C1-C4 alkyl group, a C3-C4 alkenyl group, or the like, R6 represents a hydrogen atom or the like, R7 represents a hydrogen atom or the like, R8 represents a hydrogen atom or the like, R9 represents a hydrogen atom or the like, R10 represents a hydrogen atom or the like, R11 represents a hydrogen atom or the like, and R12 represents a hydrogen atom or the like, have excellent control activities against plant diseases.