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300355-23-1

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300355-23-1 Usage

General Description

4-chloro-3-nitrophenylacetic acid methyl ester is a chemical compound that contains a methyl ester group attached to a 4-chloro-3-nitrophenylacetic acid molecule. It is a yellow crystalline solid, and its chemical formula is C9H8ClNO5. 4-chloro-3-nitrophenylacetic acid methyl ester is commonly used as an intermediate in the synthesis of pharmaceutical and agrochemical products. It is also used in organic synthesis and as a reagent in chemical research. The presence of the 4-chloro and 3-nitro groups in the molecule makes it a useful building block for the preparation of various functionalized organic compounds.

Check Digit Verification of cas no

The CAS Registry Mumber 300355-23-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,0,0,3,5 and 5 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 300355-23:
(8*3)+(7*0)+(6*0)+(5*3)+(4*5)+(3*5)+(2*2)+(1*3)=81
81 % 10 = 1
So 300355-23-1 is a valid CAS Registry Number.

300355-23-1Relevant articles and documents

Discovery of piragliatin-first glucokinase activator studied in type 2 diabetic patients

Sarabu, Ramakanth,Bizzarro, Fred T.,Corbett, Wendy L.,Dvorozniak, Mark T.,Geng, Wanping,Grippo, Joseph F.,Haynes, Nancy-Ellen,Hutchings, Stanley,Garofalo, Lisa,Guertin, Kevin R.,Hilliard, Darryl W.,Kabat, Marek,Kester, Robert F.,Ka, Wang,Liang, Zhenmin,Mahaney, Paige E.,Marcus, Linda,Matschinsky, Franz M.,Moore, David,Racha, Jagdish,Radinov, Roumen,Ren, Yi,Qi, Lida,Pignatello, Michael,Spence, Cheryl L.,Steele, Thomas,Tengi, John,Grimsby, Joseph

supporting information, p. 7021 - 7036 (2012/11/07)

Glucokinase (GK) activation as a potential strategy to treat type 2 diabetes (T2D) is well recognized. Compound 1, a glucokinase activator (GKA) lead that we have previously disclosed, caused reversible hepatic lipidosis in repeat-dose toxicology studies.

Tetrahydrocarbazol derivatives as ligands for G-protein-coupled receptors (GPCR)

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Page 13 - 14, (2010/11/30)

This invention provides new tetrahydrocarbazole derivatives that act as ligands for G-protein-coupled receptors (GPCR), especially as antagonists of the gonadotropin-releasing hormone (GnRH). A pharmaceutical composition that contains these new tetrahydro

Heteroaromatic glucokinase activators

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, (2008/06/13)

2,3-Di-substituted N-heteroaromatic propionamides with said substitution at the 2-position being a substituted phenyl group and at the 3-position being a cycloalkyl ring, said propionamides being glucokinase activators which increase insulin secretion in the treatment of type II diabetes.

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