30062-44-3Relevant articles and documents
Crystal structure of an AgClO4 π complex with 2-amino-5-allylthio-1,3,4-thiadiazole of the composition [Ag(C5H7N3S2)(ClO4)]
Slyvka, Yu. I.
, p. 356 - 357 (2017)
By interaction of AgClO4 with 2-amino-5-allylthio-1,3,4-thiadiazole (Aаtd) in the ethanol solution, a new [Ag(Aаtd)(ClO4)] π complex is obtained. It is studied by single crystal X-ray diffraction.
Design and development of 1,3,4-thiadiazole based potent new nano-fungicides
Gogoi, Robin,Kumar, Rajesh,Pal, Suprabhat,Singh, Vikrant
, (2020/06/17)
Being the important organic reaction intermediates and biological scaffolds, a series of 2-alkyl/aralkyl/heterocyclyl sulfanyl-5-amino/methyl-1,3,4-thiadiazoles have been synthesized by suitable synthetic route and characterized by analytical and spectral data. The evaluation of these compounds for their bioefficacy against two phyto-pathogenic fungi revealed their fungicidal potency against Rhizoctonia bataticola (ED50 values, 3.9–300.4 μg/mL) and Rhizoctonia solani (ED50 values, 4.2–228.5 μg/mL). To further augment their fungicidal efficacy, the potent five fungicidal compounds were nano-sized. The protocol for preparing 1,3,4-thiadiazole based nano-fungicide employing polyethylene glycol was developed and standardized. Characterization of nano-forms of 1,3,4-thiadiazole derivatives by particle size analyzer and electron microscopy (TEM) techniques confirmed the 100 nm average particle sizes of all nano-fungicides. The 2–4 times higher fungicidal activity was observed with nano-forms than the corresponding conventional sized 1,3,4-thiadiazole derivatives against phytopathogenic fungi, namely, Rhizoctonia solani and R. bataticola.