300707-60-2

Basic information

• Product Name: 2-bromo-N-(4-methylphenyl)butanamide
• Synonyms: 2-bromo-N-(4-methylphenyl)butanamide;2-bromo-N-(4-methylphenyl)butyramide
• CAS NO: 300707-60-2
• Molecular Formula: C₁₁H₁₄BrNO
• Molecular Weight: 256.13896
• Mol File: 300707-60-2.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-bromo-N-(4-methylphenyl)butanamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-bromo-N-(4-methylphenyl)butanamide(300707-60-2)
• EPA Substance Registry System: 2-bromo-N-(4-methylphenyl)butanamide(300707-60-2)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 300707-60-2(Hazardous Substances Data)

Upstream product

• 26074-52-2 2-bromo-butyryl bromide 
• 106-49-0 p-toluidine 
• 22118-12-3 2-bromobutanoyl chloride 

Downstream Products

• 162375-41-9 N-4'-methylphenyl-2-(phenylthio)butanamide 
• 123271-08-9 (Z)-N-(4-methylphenyl)-2-(phenylthio)-2-butenamide 

Relevant articles and documents

Investigation of the synthetic and mechanistic aspects of the highly stereoselective transformation of α-thioamides to α-thio-β- chloroacrylamides

Treatment of a series of α-thioamides with N-chlorosuccinimide results in efficient transformation to the analogous α-thio-β- chloroacrylamides. The mechanistic pathway has been established through isolation and characterisation of intermediate compounds. The scope of the transformation has been explored - aryl and alkylthio substituents, primary, secondary and tertiary amides can be employed. In most instances, the chloroacrylamides are formed exclusively as the Z-stereoisomer; however, with tertiary propanamides or with amides derived from butanoic or pentanoic acid a mixture of E- and Z-stereoisomers is formed. The Royal Society of Chemistry.