300814-10-2

Basic information

• Product Name: N-(furan-2-ylmethyl)-4-methoxybenzamide
• Synonyms: N-(furan-2-ylmethyl)-4-methoxybenzamide
• CAS NO: 300814-10-2
• Molecular Weight: 231.251
• Mol File: 300814-10-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-(furan-2-ylmethyl)-4-methoxybenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(furan-2-ylmethyl)-4-methoxybenzamide(300814-10-2)
• EPA Substance Registry System: N-(furan-2-ylmethyl)-4-methoxybenzamide(300814-10-2)

Safety Data

• Hazardous Substances Data: 300814-10-2(Hazardous Substances Data)

Upstream product

• 617-89-0 furan-2-ylmethanamine 
• 100-07-2 4-methoxy-benzoyl chloride 

Downstream Products

• 1231245-48-9 4-methoxy-N-((1E,3E)-5-oxopenta-1,3-dienyl)benzamide 
• 225236-03-3 1-(furan-2-yl)-N-(4-methoxybenzyl)methanamine 

Relevant articles and documents

Reduction of selenoamides to amines using SmI2-H2O

Selenoamides are selectively reduced to amines by SmI2 with H2O. The process is general for primary, secondary, and tertiary aryl and alkyl selenoamide substrates and selectively delivers amine products. The reduction proceeds under mild conditions using SmI2 activated by straightforward addition of H2O, and does not require an additional Lewis base additive.

Synthesis of N -Acyl-5-aminopenta-2,4-dienals via base-induced ring-opening of N -acylated furfurylamines: Scope and limitations

N-Acylation of furfurylamines provided 1, which on double deprotonation with LDA led to the formation of N-acyl-5-aminopenta-2,4-dienals 2 via an isomerization involving opening of the furan ring. The scope and limitations of the procedure were examined by considering the influence of substituents on the carbonyl group and also on the heterocycle moiety. The efficacy of the reaction was shown to be very dependent on the nature of these groups.