30162-68-6

Basic information

• Product Name: 3(2H)-Isothiazolethione, 2-methyl-5-phenyl-
• CAS NO: 30162-68-6
• Molecular Formula: C10H9NS2
• Molecular Weight: 207.32
• Mol File: 30162-68-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3(2H)-Isothiazolethione, 2-methyl-5-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 3(2H)-Isothiazolethione, 2-methyl-5-phenyl-(30162-68-6)
• EPA Substance Registry System: 3(2H)-Isothiazolethione, 2-methyl-5-phenyl-(30162-68-6)

Safety Data

• Hazardous Substances Data: 30162-68-6(Hazardous Substances Data)

Upstream product

• 56617-74-4 N-methyl-3-oxo-3-phenyl-propanethioamide 
• 66196-20-1 2-methyl-5-phenyl-4-isoxazolin-3-thione 
• 4849-59-6 5-phenyl-3-methylthio-1,2-dithiolium iodide 
• 74-89-5 methylamine 
• 16794-54-0 3-methylimino-5-phenyl-1,2-dithiol 
• 74-88-4 methyl iodide 
• 21305-56-6 3-methylthio-4-phenyl-1,2-dithiolium iodide 
• 1075-21-4 5-phenylisothiazole 
• 77-78-1 dimethyl sulfate 

Downstream Products

• 282111-08-4 N-ethyl-N-methoxycarbonyl-N'-ethyl-N'-(3-methylamino-5-phenyl-2-thenoyl)thiourea 
• 282110-91-2 cis-ethyl 3-(3-methylamino-5-phenylthenoyl)-2-propenoate 
• 282110-99-0 ethyl 2-(3-methylamino-5-phenyl-2-thenoyl)phenyloxoacetate 

Relevant articles and documents

A facile and convenient synthesis of 3-alkylamino-5-arylthiophenes with a variety of substituents at C-2 and studies of reaction mechanisms

Thioaroylketene S,N-acetals were treated with active methylene compounds including β-keto ester, nitromethane, cyanoacetic acid, p- toluenesulfonylacetone, 4-nitrophenylacetic acid, and diethyl (2- oxopropyl)phosphonate in the presence of mercury(II) acetate in CH2Cl2 at room temperature. These reactions gave 3-alkylamino-5-arylthiophenes containing various substituents, which comprised, respectively, alkoxycarbonyl, nitro, cyano, p-toluenesulfonyl, 4-nitrophenyl, and diethylphosphono groups at C-2 in good yields. The reaction of 3-methylamino- 3-methylthio-1-phenylthioxopropene with malonic acid or Meldrum's acid under the same conditions gave 3-methylamino-5-phenylthiophene. Similarly, treatment of 3-methylamino-3-methylthio-1-phenylthioxopropene with various enolizable cyclic ketones such as 4-hydroxy-6-methyl-2-pyrone, homophthalic anhydride, 2-hydroxy1,4-benzoquinone, and 1,3-diethyl-2-thiobarbituric acid gave thieno[3,2-b]pyridin-4-one, thieno[3,2c]isoquinolin-5-one, thieno[3,2- c]benzazepine-1,6-dione, and thieno[3,2-d]pyrimidine-2,4-dione, respectively.