301668-92-8Relevant articles and documents
A selective triarylmethine-based spectroscopic probe for Zn2+ ion monitoring
Lee, Naru,Ly, Nguyen Hoang,Kim, Jong Seung,Jung, Hyo Sung,Joo, Sang-Woo
, (2019)
We report the synthesis and application of a novel probe of the di-2-picolylamine (DPA)-conjugated triarylmethine (TAM) dye which has aimed at detecting Zn2+ ions. The 1:2 binding stoichiometry is estimated between Zn2+ and DPA-TAM a
A selective fluorescent sensor for imaging Cd2+ in living cells
Peng, Xiaojun,Du, Jianjun,Fan, Jiangli,Wang, Jingyun,Wu, Yunkou,Zhao, Jianzhang,Sun, Shiguo,Xu, Tao
, p. 1500 - 1501 (2007)
A selective sensor 1 for the fluorescent imaging of Cd2+ in living cells has been designed and synthesized based on an internal charge transfer (ICT) mechanism. It can distinguish Cd2+ from Zn2+ and can be used in both general fluorescence intensity microscopy and ratiometric fluorescence microscopy. Copyright
New Sensitive and Selective Chemical Sensors for Ni2+and Cu2+Ions: Insights into the Sensing Mechanism through DFT Methods
Hidalgo-Rosa, Yoan,Molins, Elies,Páez-Hernández, Dayan,Schott, Eduardo,Tapia, Jorge,Treto-Suárez, Manuel A.,Zarate, Ximena
, p. 6493 - 6503 (2020)
We report the synthesis and theoretical study of two new colorimetric chemosensors with special selectivity and sensitivity to Ni2+ and Cu2+ ions over other metal cations in the CH3CN/H2O solution. Compounds (E)-4-((2-nitrophenyl)diazenyl)-N,N-bis(pyridin-2-ylmethyl)aniline (A) and (E)-4-((3-nitrophenyl)diazenyl)-N,N-bis(pyridin-2-ylmethyl)aniline (B) exhibited a drastic color change from yellow to colorless, which allows the detection of the mentioned metal cations through different techniques. The interaction of sensors with these metal ions induced a new absorption band with a hypsochromic shift to the characteristic signal of the free sensors. A theoretical study via time-dependent density functional theory (TD-DFT) was performed. This method has enabled us to reproduce the hypsochromic shift in the maximum UV-vis absorption band and explain the selective sensing of the ions. For all of the systems studied, the absorption band is characterized by a π→ π? transition centered in the ligand. Instead of Ni2+ and Cu2+ ions, the transition is set toward the σ? molecular orbital with a strong contribution of the 3dx2-y2 transition (π→ 3dx2-y2). These absorptions imply a ligand-to-metal charge transfer (LMCT) mechanism that results in the hypsochromic shift in the absorption band of these systems.
Colorimetric indicators for specific recognition of Cu2+ and Hg2+ in physiological media: Effect of variations of signaling unit on optical response
Dey, Nilanjan,Kumari, Namita,Biswakarma, Dipen,Jha, Satadru,Bhattacharya, Santanu
, p. 50 - 57 (2019)
Easy to synthesize probes are designed using bispicolyl moiety as the receptor unit with two different signaling moieties, anthraquinone and bisindolyl. Both the compounds show ‘naked-eye’ sensing of Cu2+ and Hg2+ in ～100% aqueous me
A highly sensitive chemosensor for rapid recognition of Cu2+ and HSO3? in 100% aqueous solution
Chen, Hongbiao,Li, Huaming,Liu, Shuzhi,Liu, Yijiang,Ou, Zhipeng
, (2021/07/31)
Dual-responsive chemosensors have garnered much research interests owing to the ability of recognizing two analytes simultaneously. Herein, the chemosensor BPIS composed of hemicyanine and 2, 2′-dipyridylamine (DPA) was facilely synthesized for sensitive and expeditious recognition of Cu2+ and HSO3? in 100% aqueous solution. By adding Cu2+, BPIS showed substantial spectral changes accompanied by a noticeable color change from pink to yellow under daylight. The absorbance and fluorescence intensity were linearly correlated to the Cu2+ concentration, enabling the quantitative recognition of Cu2+. The limit of detection (LOD) for Cu2+ was down to 4.02 × 10?9 M. The response time of BPIS towards Cu2+ was 10 s, imparting BPIS great potential in real-time detection of Cu2+. Meanwhile, BPIS manifested ratiometric fluorescence response by introducing HSO3? owing to the 1,4-addition between HSO3? and the unsaturated C[dbnd]C bond of BPIS. The color of the BPIS solution progressively faded from pink to colorless with increasing HSO3? concentration, and a LOD of 3.47 × 10?9 M was obtained. In addition, BPIS-coated test paper was found to be an efficient tool for fast, sensitive, portable detection of Cu2+ and HSO3? by naked eyes. More importantly, the precise detection of Cu2+ and HSO3? in real water and sugars were realized, respectively, by capitalizing on BPIS as the signal tool.
Protic media enhanced protodeboronation for a potential H2O2-sensitive ligand system
Mathis, Cheryl L.,Saouma, Caroline T.
supporting information, (2020/02/11)
The detection of elevated concentrations of reactive oxygen species (ROS) such as H2O2 represents a promising route to identify oxidative misregulation in cells, a hallmark of carcinoma and neurodegeneration. Magnetic resonance imaging (MRI) presents an opportunity to detect ROS over a greater portion of the body compared to strategies such as fluorescence. To sense hydrogen peroxide, potential Fe2+ and Co2+ MRI sensors were synthesized by appending pinacolborane to two amino-pyridine ligand scaffolds. These were designed to expose phenol upon reaction with H2O2, turning on PARACEST (Paramagnetic Chemical Exchange Saturation Transfer) and allowing detection by MRI. Instead of yielding a phenol upon exposure to oxidative conditions, protodeboronation was observed as the major product even under mild conditions. Optimization of oxidation conditions allowed access to the phenolic analogue of the two ligands studied in 11% and 17% conversion under organic conditions. Treatment of the Fe2+ and Co2+ complexes with H2O2 resulted in rapid, partial demetallation with no evidence of the bound or free ligand undergoing an oxidative transformation. These results stress the importance of establishing stability of potential MRI contrast agents in aqueous conditions.
