3019-17-8Relevant articles and documents
Features of the synthesis of S-monobenzyl and S,O-dibenzyl, di(m-phenoxybenzyl) derivatives of 6-methyl-2-thiouracil
Rakhimov,Popov,Titova
, p. 1242 - 1243 (2005)
-
Studies on solubility and S-alkylation of 2-thiouracil in ionic liquids
Nestor, Stephen T.,Hawkins, Allison N.,Xhani, Xhensila,Sykora, Richard E.,Mao, James X.,Nam, Kwangho,McManus, Gregory J.,Mirjafari, Arsalan
, p. 463 - 467 (2018)
Ionic liquids have been exploited to assist dissolution of poorly soluble (and poorly bioavailable) drugs, enhancing permeation through physiological barriers to deliver drugs to target sites. Herein, the solubility of 6-methyl-2-thiouracil – a common ant
HEPATITIS B VIRAL ASSEMBLY EFFECTORS
-
Paragraph 00137; 00138, (2015/05/05)
Novel assembly effector compounds having a therapeutic effect against hepatitis B viral (HBV) infection are disclosed. Assembly effector molecules described herein can lead to defective viral assembly and also may affect other viral activities associated with chronic HBV infection. Also disclosed is a process to synthesize disclosed compounds, method of treatment of HBV by administration of disclosed compounds, and use of these compounds in the manufacture of medicaments against HBV.