303-80-0 Usage
Description
10-Hydroxy-5-oxido-phenazin-2-one is an organic compound with the molecular formula C12H7NO4. It belongs to the phenazine family of compounds, which are known for their diverse range of biological activities. This particular compound is characterized by the presence of a hydroxyl group at the 10th position and an oxido group at the 5th position, along with a phenazin-2-one core structure.
Uses
Used in Pharmaceutical Industry:
10-Hydroxy-5-oxido-phenazin-2-one is used as an intermediate in the synthesis of various pharmaceutical compounds, particularly those with antimicrobial properties. Its unique chemical structure allows for the development of new drugs that can effectively target and combat a wide range of bacterial and fungal infections.
Used in Antimicrobial Applications:
10-Hydroxy-5-oxido-phenazin-2-one is used as an active ingredient in the development of quinoxaline 1,4-dioxide derivatives for antimicrobial treatments. These derivatives exhibit potent antimicrobial activity against various pathogens, making them valuable in the development of new antibiotics and antifungal agents to combat drug-resistant infections.
Check Digit Verification of cas no
The CAS Registry Mumber 303-80-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,0 and 3 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 303-80:
(5*3)+(4*0)+(3*3)+(2*8)+(1*0)=40
40 % 10 = 0
So 303-80-0 is a valid CAS Registry Number.
InChI:InChI=1/C12H8N2O3/c15-8-5-6-11-12(7-8)14(17)10-4-2-1-3-9(10)13(11)16/h1-7,15H
303-80-0Relevant articles and documents
Formyl substituted phenazine 5,10 dioxides
Edwards,Bambury,Kim
, p. 653 - 656 (1976)
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Synthesis of phenazine 5,10-dioxides from benzofuroxan catalyzed by molecular sieves
Takabatake, Tohru,Miyazawa, Tomoyuki,Kojo, Mahiro,Hasegawa, Minoru
, p. 2151 - 2162 (2000)
The synthesis of substituted phenazines was carded out. Phenazine 5,10-dioxides (3) were obtained from benzofuroxan (1) with dihydroxybenzene derivatives (2) catalyzed by molecular sieves at room temperature.
A new Route for the Synthesis of Phenazine Di-N-Oxides
El-Halim, M. S. Abd,El-Ahl, A. S.,Etman, H. A.,Ali, M. M.,Fouda, A.,Fadda, A. A.
, p. 1217 - 1224 (2007/10/03)
Several phenazine 5,10-dioxides (7a-d) were prepared by the reaction of 2-methyl-3-acetylquinoxaline 1,4-dioxide (2) with different aromatic aldehydes or by direct cyclization of the quinoxaline cinnamoyl derivatives 3 in basic medium.In addition, the phe
