303111-41-3

Basic information

• Product Name: (S)-1-BENZYL-3-N-BOC-AMINOMETHYLPYRROLIDINE
• Synonyms: (S)-1-BENZYL-3-N-BOC-AMINOMETHYLPYRROLIDINE;(S)-1-Benzyl-3-N-Boc-aminometylpyrrolidine;tert-butyl N-[[(3S)-1-benzylpyrrolidin-3-yl]methyl]carbamate;tert-butyl(S)-((1-benzylpyrrolidin-3-yl)methyl)carbamate
• CAS NO: 303111-41-3
• Molecular Formula: C₁₇H₂₆N₂O₂
• Molecular Weight: 290.41
• Mol File: 303111-41-3.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 400.1 °C at 760 mmHg
• Flash Point: 195.8 °C
• Appearance: /
• Density: 1.059 g/cm³
• Vapor Pressure: 1.3E-06mmHg at 25°C
• Refractive Index: 1.527
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (S)-1-BENZYL-3-N-BOC-AMINOMETHYLPYRROLIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1-BENZYL-3-N-BOC-AMINOMETHYLPYRROLIDINE(303111-41-3)
• EPA Substance Registry System: (S)-1-BENZYL-3-N-BOC-AMINOMETHYLPYRROLIDINE(303111-41-3)

Safety Data

• Hazardous Substances Data: 303111-41-3(Hazardous Substances Data)

Usage

General Description

(S)-1-Benzyl-3-N-BOC-aminomethylpyrrolidine is a chemical compound that belongs to the class of amines and is commonly used in organic synthesis and pharmaceutical research. It is a chiral compound with a benzyl group attached to the nitrogen atom and a BOC (tert-butoxycarbonyl) protecting group on the amino group. (S)-1-BENZYL-3-N-BOC-AMINOMETHYLPYRROLIDINE is known for its potential in creating diverse molecules due to its reactivity and ability to participate in various organic reactions. Its unique structure and chirality make it an important intermediate in the synthesis of biologically active molecules and pharmaceuticals. Due to its versatile nature and potential applications, (S)-1-Benzyl-3-N-BOC-aminomethylpyrrolidine is a valuable compound in chemical and pharmaceutical industries.

InChI:InChI=1/C17H26N2O2/c1-17(2,3)21-16(20)18-11-15-9-10-19(13-15)12-14-7-5-4-6-8-14/h4-8,15H,9-13H2,1-3H3,(H,18,20)/t15-/m0/s1

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 229323-07-3 (R)-C-(1-benzyl-pyrrolidin-3-yl)-methylamine 

Downstream Products

• 303111-42-4 ((S)-1-Benzyl-pyrrolidin-3-ylmethyl)-methyl-amine 
• 173340-25-5 (R)-1-pyrrolidin-3-ylmethylcarbamic acid tert-butyl ester 

Relevant articles and documents

QUINOLONE ANTIBACTERIAL AGENTS

Compounds of formula (I) wherein A is formula (II), formula (III) or formula (IV), and B is formula (V), formula (VI), or formula (VII), can be used in a variety of applications including use as antibacterial agents.

Phenyloxazoles and phenylthiazoles as benzamide bioisosteres: Synthesis and dopamine receptor binding profiles

Conformationally restricted benzamide bioisosteres were investigated when the aminomethylpyrrolidine derivative 4o proved D3 as well as D4 binding properties which were comparable to those of the atypical neuroleptics sulpiride and clozapine, respectively. (C) 2000 Elsevier Science Ltd.