303128-79-2

Basic information

• Product Name: 3β-hydroxy-16-p-chlorobenzylidene-5α-androstan-17-one
• Synonyms: 3β-hydroxy-16-p-chlorobenzylidene-5α-androstan-17-one
• CAS NO: 303128-79-2
• Molecular Weight: 413
• Mol File: 303128-79-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3β-hydroxy-16-p-chlorobenzylidene-5α-androstan-17-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3β-hydroxy-16-p-chlorobenzylidene-5α-androstan-17-one(303128-79-2)
• EPA Substance Registry System: 3β-hydroxy-16-p-chlorobenzylidene-5α-androstan-17-one(303128-79-2)

Safety Data

• Hazardous Substances Data: 303128-79-2(Hazardous Substances Data)

Upstream product

• 481-29-8 Epiandrosterone 
• 104-88-1 4-chlorobenzaldehyde 
• 1239-31-2 3β-acetoxy-5α-androstan-17-one 

Downstream Products

• 1310799-03-1 16-(4-chloro-benzylidene)-3β-morpholino-5α-androstan-17β-yl acetate 
• 1310799-04-2 16-(4-chloro-benzylidene)-3β-(4-methylpiperazinyl)-5α-androstan-17β-yl acetate 
• 1312542-76-9 16-(4-chloro-benzylidene)-5α-androstan-3,17-dione 
• 1312542-91-8 16-(4-chloro-benzylidene)-3β-piperidino-5α-androstan-17-one 
• 1312542-92-9 16-(4-chloro-benzylidene)-3β-pyrrolidino-5α-androstan-17-one 
• 1312542-93-0 16-(4-chloro-benzylidene)-3β-morpholino-5α-androstan-17-one 
• 1312542-94-1 16-(4-chloro-benzylidene)-3β-(4-methylpiperazinyl)-5α-androstan-17-one 
• 1312543-18-2 16-(4-chloro-benzylidene)-3β-piperidino-5α-androstan-17β-ol 
• 1312543-19-3 16-(4-chloro-benzylidene)-3β-pyrrolidino-5α-androstan-17β-ol 
• 1312543-20-6 16-(4-chloro-benzylidene)-3β-morpholino-5α-androstan-17β-ol 
• 1312543-21-7 16-(4-chloro-benzylidene)-3β-(4-methylpiperazinyl)-5α-androstan-17β-ol 
• 1310799-01-9 16-(4-chloro-benzylidene)-3β-piperidino-5α-androstan-17β-yl acetate 
• 1310799-02-0 16-(4-chloro-benzylidene)-3β-pyrrolidino-5α-androstan-17β-yl acetate 
• 1428382-43-7 C₄₁H₄₄ClNO₃S 

Relevant articles and documents

Synthesis of novel 16-spiro steroids: Spiro-7′-(aryl)tetrahydro-1H- pyrrolo[1,2-c][1,3]thiazolo-trans-androsterone hybrid heterocycles

The 1,3-dipolar cycloaddition of azomethine ylide derived in situ from the reaction of acenaphthylene-1,2-dione and 1,3-thiazolane-4-carboxylic acid to various exocyclic dipolarophiles synthesized from trans-androsterone and trans-dehydroandrosterone afforded a library of novel spiro[5′.2″] acenaphthylene-1″-one-spiro[16.6′]-(7′-aryl) -tetrahydro-1H-pyrrolo [1,2-c][1,3]thiazolo-trans-androsterone/ dehydroandrosterone hybrid heterocycles respectively. These reactions proceeded stereo-specifically affording a single isomer of the 16-spiro steroids in excellent yields.

Peracid Oxidation of 16-Arylidene- and 16-Alkylidene-17-oxo-steroids

Peracid oxidation of 16-arylidene- and 16-alkylidene-5α-androstan-17-ones (1) - (6) gave no α,β-unsaturated δ-lactones, but resulted mainly in products of direct oxidation of the olefinic double bond.