30313-22-5

Basic information

• Product Name: (2E,4E)-1-(4-methylphenyl)-5-phenylpenta-2,4-dien-1-one
• CAS NO: 30313-22-5
• Molecular Formula: C₁₈H₁₆O
• Molecular Weight: 248.319
• Mol File: 30313-22-5.mol
• Article Data: 22

Chemical Properties

• Boiling Point: 413.4°C at 760 mmHg
• Flash Point: 181.3°C
• Density: 1.067g/cm³
• Vapor Pressure: 4.81E-07mmHg at 25°C
• Refractive Index: 1.615
• CAS DataBase Reference: (2E,4E)-1-(4-methylphenyl)-5-phenylpenta-2,4-dien-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (2E,4E)-1-(4-methylphenyl)-5-phenylpenta-2,4-dien-1-one(30313-22-5)
• EPA Substance Registry System: (2E,4E)-1-(4-methylphenyl)-5-phenylpenta-2,4-dien-1-one(30313-22-5)

Safety Data

• Hazardous Substances Data: 30313-22-5(Hazardous Substances Data)

Usage

Description

(2E,4E)-1-(4-methylphenyl)-5-phenylpenta-2,4-dien-1-one is a yellow solid with a molecular formula of C17H14O and a molecular weight of 234.29 g/mol. It belongs to the benzophenone class of chemicals and is known for its potential biological activities, including antioxidant, antimicrobial, and anticancer properties.

Uses

Used in Pharmaceutical Industry:
(2E,4E)-1-(4-methylphenyl)-5-phenylpenta-2,4-dien-1-one is used as a building block for the synthesis of pharmaceuticals due to its potential biological activities, including antioxidant, antimicrobial, and anticancer properties.
Used in Agrochemical Industry:
(2E,4E)-1-(4-methylphenyl)-5-phenylpenta-2,4-dien-1-one is used as a building block for the synthesis of agrochemicals due to its potential biological activities, including antioxidant, antimicrobial, and anticancer properties.
Used in Organic Compounds Synthesis:
(2E,4E)-1-(4-methylphenyl)-5-phenylpenta-2,4-dien-1-one is used as a building block in the synthesis of various organic compounds due to its unique chemical structure and properties.

Upstream product

• 122-00-9 para-methylacetophenone 
• 101194-49-4 diethyl (1E,3E)-(1-methylsulfonyl-4-phenyl-1,3-butadienyl)phosphonate 
• 104-55-2 3-phenyl-propenal 
• 14371-10-9 (E)-3-phenylpropenal 
• 108-86-1 bromobenzene 
• 874-60-2 4-methyl-benzoyl chloride 
• 300-57-2 allylbenzene 

Downstream Products

• 30314-04-6 5-styryl-3-p-tolyl-cyclohex-2-enone 
• 65-85-0 benzoic acid 
• 55860-86-1 2,3,3-triphenyl-4-(4-phenyl-buta-1,3-dienyl)-4-p-tolyl-[1,2]oxaphosphetane 2-oxide 
• 60367-15-9 1,2-bis(diphenylphosphinoxido)-1,2-diphenylethane 
• 55911-53-0 1,1,6-Triphenyl-2-(p-tolyl)-1,3,5-hexatrien 
• 26191-85-5 7-exo-Diphenylphosphoryl-7-endo-phenylnorcaradien 
• 55860-86-1 2,3,3-Triphenyl-4-(4-phenyl-1,3-butadienyl)-4-(p-tolyl)-1,2λ⁵-oxaphosphetan-2-on 
• 141368-97-0 3a,4-Bis-((E)-styryl)-2,6-di-p-tolyl-3a,4-dihydro-[1,2]thiaphospholo[2,3-b][1,2]thiaphosphinine 8-sulfide 
• 296759-72-3 3-(4-methylbenzoyl)-4-styryl-2-pyrazoline 

Relevant articles and documents

Palladium-Catalyzed Aminomethylation of Nitrodienes and Dienones via Double C—N Bond Activation

A new strategy for the generation of the active Pd-alkyl species from aminal via C—N bond activation has been established, in which the formation of zwitterionic intermediate through aza-Michael addition of aminal to nitrodienes or dienones is identified as a key step for the activation of the C—N bond. The efficient strategy has enabled a new palladium-catalyzed α-aminomethylation of nitrodienes and dienones via double C—N bond activation. The scope and versatility of the reaction were demonstrated and a broad range of substrates bearing electron-donating and -withdrawing groups on the aromatic rings were all compatible with this reaction to furnish the desired α-aminomethylated products in moderate to good yields with excellent regioselectivities and E/Z selectivities.

Antibacterial & antitubercular activities of cinnamylideneacetophenones

Cinnamaldehyde is a natural product with broad spectrum of antibacterial activity. In this work, it was used as a template for design and synthesis of a series of 17 cinnamylideneacetophenones. Phenolic compounds 3 and 4 exhibited MIC (minimum inhibitory

Further studies on anti-invasive chemotypes: An excursion from chalcones to curcuminoids

In our ongoing search for new anti-invasive chemotypes, we have made an excursion from previously reported potent 1,3-diarylpropenones (chalcones) to congeners bearing longer linkers between the aromatic moieties. Nine 1,ω-diarylalkenones, including curcumin and bisdemethoxycurcumin, were evaluated in the chick heart invasion assay. Unfortunately, these compounds proved less potent and more toxic than earlier evaluated chemotypes. In the 1,3-diarylpenta-2,4-dien-1-one series, fluoro and/or trimethoxy substitution caused an increase in potency. This agrees with observations made earlier for the chalcone class.