30315-46-9Relevant articles and documents
A Strategy for the Transformation of a Multifunctional Chiral Synthon of Moderate ee into an Enantiomerically Pure Synthetic Intermediate
D'Arrigo, Paola,Feliciotti, Luca,Pedrocchi-Fantoni, Giuseppe,Servi, Stefano
, p. 6394 - 6396 (2007/10/03)
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Stereoselective synthesis of the β2-adrenergic blocking agent IPS 339 from optically active precursors
Leclerc,Amlaiky,Rouot
, p. 69 - 74 (2007/10/02)
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1-SUBSTITUTED AMINO-3-THIENO-[3,2-c]PYRIDINYLOXY-2-PROPANOLS
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, (2008/06/13)
This invention provides new compounds of formula I, STR1 wherein X is sulphur or oxygen,R is alkyl of 3 to 7 carbon atoms or cycloalkyl of 3 to 7 carbon atoms, cycloalkyl of 3 to 7 carbon atoms monosubstituted by alkyl of 1 to 4 carbon atoms, α-dialkylpropinyl of 5 to 9 carbon atoms or α-dialkyl-allyl of 5 to 9 carbon atoms, hydroxyalkyl of 2 to 7 carbon atoms or phenoxyalkyl of 8 to 11 carbon atoms, the oxygen atom of the last two radicals being separated by at least two carbon atoms from the nitrogen atom to which R is bound, R 1 isI. hydrogen or alkyl of 1 to 4 carbon atoms in the 2,3,6 or 7 position, orIi. chlorine or bromine, in the 2, 3 or 7 position,Iii. nitro or--NHA wherein A is alkanoyl of 1 to 4 carbon atoms, in the 2, 3 or 7 position, orIv. fluorine, cyano or COOB, wherein B is alkyl of 1 to 4 carbon atoms, in the 2 or 3 position, andR 2 isI. hydrogen or alkyl of 1 to 4 carbon atoms in the 2, 3, 6 or 7 position,Ii. chlorine or bromine, in the 2, 3 or 7 position, orIii. fluorine in the 2 or 3 position,Useful in the treatment of heart diseases.