30318-36-6

Basic information

• Product Name: N,N-DiMethyl BenzilaMide
• Synonyms: N,N-DiMethyl BenzilaMide;α-Hydroxy-N,N-diMethyl-α-phenylbenzeneacetaMide
• CAS NO: 30318-36-6
• Molecular Formula: C₁₆H₁₇NO₂
• Molecular Weight: 255
• Product Categories: Amines;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;Amines, Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 30318-36-6.mol
• Article Data: 4

Chemical Properties

• Melting Point: 131-132 °C
• Boiling Point: 434.7±45.0 °C(Predicted)
• Appearance: /
• Density: 1.154±0.06 g/cm3(Predicted)
• PKA: 11.65±0.29(Predicted)
• CAS DataBase Reference: N,N-DiMethyl BenzilaMide(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-DiMethyl BenzilaMide(30318-36-6)
• EPA Substance Registry System: N,N-DiMethyl BenzilaMide(30318-36-6)

Safety Data

• Hazardous Substances Data: 30318-36-6(Hazardous Substances Data)

Usage

Uses

Loperamide (L469450) impurity.

Upstream product

• 957-51-7 diphenamid 
• 63953-26-4 2-bromo-N,N-dimethyl-2,2-diphenylacetamide 
• 35451-97-9 N,N-dimethyl-2-chloro-2,2-diphenylacetamide 
• 72572-07-7 N,N-dimethyl-2,2-diphenyl-2-(phenylazo)acetamide 
• 77-76-9 2,2-dimethoxy-propane 
• 51579-87-4 N,N-dimethyl-2-oxo-2-phenylacetamide 
• 100-58-3 phenylmagnesium bromide 
• 68-12-2 N,N-dimethyl-formamide 
• 134-81-6 benzil 
• 25726-04-9 phenylglyoxylyl chloride 

Relevant articles and documents

Base-induced rearrangement of O-benzoylbenzaldehyde cyanohydrin to benzil and the further reactions of benzil

O-Benzoylbenzaldehyde cyanohydrin has been found to form benzil in DMF in a base-catalysed reversible reaction. The possibility of using the reaction for the synthesis of unsymmetrical benzils from an aldehyde derivative and an acid derivative was investigated, but such a synthesis was made invalid by the further reaction of benzil with strong bases. The reaction of benzil with potassium tertbutoxide in DMF gave several products, among which the formation of two of them involved the anion of DMF and the formation of others included redox reactions. Acta Chemica Scandinavica 1998.

Single-electron Transfer-initiated Thermal Reactions of Arylmethyl Halides, IX. The Reaction of 2-Bromo-N,N-dimethyl-2,2-diphenylacetamide with Triethylamine in Benzene

Das Halogenamid 1a liefert mit Triethylamin in siedendem Benzol 41-48percent des Dimeren 3 als Hauptprodukt.Andererseits fuehrt die Thermolyse von 1f in Benzol in Gegenwart von Triethylamin zu 1c und 8a.Die Bildung von 3 erfolgt ueber die Radikale 4, die ihrerseits das Produkt einer Ein-Elektronen-Uebergangs-Reaktion mit Triethylamin als Elektron-Donor sind.Der Uebergang der Radikale 4 in das Dimere 3 verlaeuft entsprechend der Reaktionsfolge (2)+(4)+(5) (carbanionischer Mechanismus der Dimeren-Bildung).