30379-55-6 Usage
Description
Benzyloxyacetic acid is a colorless liquid compound that is utilized in various fields due to its unique chemical properties. It is known for its in vitro activities as antisickling agents and has been investigated through quantitative structure-activity relationship (QSAR) of Hansch-type.
Uses
1. Used in Proteomics Research:
Benzyloxyacetic acid is used as a compound for proteomics research, which is essential for understanding the structure, function, and interactions of proteins within a biological system.
2. Used in Chemical Synthesis:
Benzyloxyacetic acid is used as a key component in the synthesis of various compounds, such as mixed benzyloxyacetic pivalic anhydride, chiral glycolates, and 1,2:4,5-di-O-isopropylidene-β-D-fructopyranos-3-yl benzyloxyacetate. These syntheses are achieved through esterification, a chemical reaction that involves the formation of an ester from an alcohol and an acid.
3. Used in the Preparation of Metal Complexes:
Benzyloxyacetic acid serves as a ligand in the preparation of diaquabis(benzyloxyacetato)copper(II) complex. This complex is a coordination compound that consists of a central metal ion (copper in this case) surrounded by ligands, which are molecules or ions that donate electrons to the metal center.
4. Used in Pharmaceutical Industry:
The in vitro activities of phenoxy and benzyloxyacetic acid derivatives as antisickling agents have been investigated, which could potentially lead to the development of new treatments for sickle cell disease and other related conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 30379-55-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,0,3,7 and 9 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 30379-55:
(7*3)+(6*0)+(5*3)+(4*7)+(3*9)+(2*5)+(1*5)=106
106 % 10 = 6
So 30379-55-6 is a valid CAS Registry Number.
InChI:InChI=1/C9H10O3/c10-9(11)7-12-6-8-4-2-1-3-5-8/h1-5H,6-7H2,(H,10,11)
30379-55-6Relevant articles and documents
On the electron withdrawing nature of ethers in glycosylation chemistry
Marqvorsen, Mikkel H.S.,Brink?, Anne,Jensen, Henrik H.
, (2020)
The present paper is a commentary on the electronic effects that protecting groups exert on glycosylation chemistry. Specifically, its purpose is to rectify the misguided use of the term electron donating benzyl groups, which hardly makes sense in the context of protecting groups on alcohols in saturated systems such as carbohydrates. It is argued that benzyl ethers (OBn) should rightfully be referred to as being inductively electron withdrawing, even if they are less so than benzoyl esters (OBz).
Toward the stereoselective synthesis of zaragozic acid framework: A desilylation-aldol reaction approach
Kurniawan, Yudhi D.,Tuck, Kellie L.,Castillón, Sergio,Robinson, Andrea J.
supporting information, (2021/11/08)
A convergent synthesis of the C3-C8 fragment of zaragozic acids is described. The key reactions include desilylation-aldol reaction, rearrangement induced by regioselective reductive cleavage, BAIB/TEMPO-Pinnick oxidation, esterification, silylation, and hydrogenolysis.
Oxidation of Primary Alcohols and Aldehydes to Carboxylic Acids via Hydrogen Atom Transfer
Tan, Wen-Yun,Lu, Yi,Zhao, Jing-Feng,Chen, Wen,Zhang, Hongbin
supporting information, p. 6648 - 6653 (2021/09/08)
The oxidation of primary alcohols and aldehydes to the corresponding carboxylic acids is a fundamental reaction in organic synthesis. In this paper, we report a new chemoselective process for the oxidation of primary alcohols and aldehydes. This metal-free reaction features a new oxidant, an easy to handle procedure, high isolated yields, and good to excellent functional group tolerance even in the presence of vulnerable secondary alcohols and tert-butanesulfinamides.