30379-57-8Relevant articles and documents
Degradable gemini quaternary ammonium salt bactericide and preparation method thereof
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Paragraph 0009, (2016/11/17)
The invention discloses a degradable gemini quaternary ammonium salt bactericide and a preparation method thereof. The method comprises steps as follows: Step one, N,N-dimethyl glycine, long-chain fatty alcohol (carbon atom numbers are 8, 10, 12, 14, 16 and 18) and benzyl alcohol have an esterification reaction in the presence of a coupling reagent to produce corresponding N,N-dimethyl glycine ester; Step two, the obtained N,N-dimethyl glycine ester and hydrogen chloride, hydrogen bromide or hydrogen iodide react to produce corresponding salt; Step three, products obtained in previous two steps and epichlorohydrin are subjected to quaternization, and degradable gemini quaternary ammonium salt is obtained. The gemini quaternary ammonium salt is more beneficial to adsorption of bacterium surfaces by bactericide molecules due to the electrostatic interaction of two quaternary nitrogen ions contained in molecules and the induction of carbonyl groups in ester groups, so that bacteria are broken through change of permeability of cell walls; hydrophilic groups and hydrophobic groups extend into lipoid layers and protein layers of bacterium cells more conveniently to cause protein denaturation and enzyme deactivation. The bactericide has higher bactericidal ability under the synergistic effect. The gemini quaternary ammonium salt bactericide is efficient, low in toxicity, easily degradable and environment-friendly.
