304-17-6

Basic information

• Product Name: N-Isopropylphthalimide
• Synonyms: 1H-Isoindole-1,3(2H)-dione,2-(1-methylethyl)-;2-(1-methylethyl)-1h-isoindole-3(2h)-dione;2-Isopropyl-isoindole-1,3-dione;n-isopropilftalimmide;n-isopropylftalimid;n-isopropyl-phthalimid;N-ISOPROPYL PHTHALIMIDE;ISOPROPYLPHTHALIMIDE
• CAS NO: 304-17-6
• Molecular Formula: C₁₁H₁₁NO₂
• Molecular Weight: 189.21
• EINECS: 206-150-5
• Product Categories: Derivatives of phthalimide
• Mol File: 304-17-6.mol
• Article Data: 28

Chemical Properties

• Melting Point: 82-84°C
• Boiling Point: 273°C(lit.)
• Flash Point: 121.1 °C
• Appearance: slight yellow liquid
• Density: 1.1596 (rough estimate)
• Vapor Pressure: 0.00253mmHg at 25°C
• Refractive Index: 1.5012 (estimate)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: -2.15±0.20(Predicted)
• CAS DataBase Reference: N-Isopropylphthalimide(CAS DataBase Reference)
• NIST Chemistry Reference: N-Isopropylphthalimide(304-17-6)
• EPA Substance Registry System: N-Isopropylphthalimide(304-17-6)

Safety Data

• RTECS: TI5425000
• Hazardous Substances Data: 304-17-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H11NO2/c1-7(2)12-10(13)8-5-3-4-6-9(8)11(12)14/h3-7H,1-2H3

Upstream product

• 85-44-9 phthalic anhydride 
• 75-31-0 isopropylamine 
• 100613-92-1 N-(2-bromo-ethyl)-N'-isopropyl-phthalamide 
• 1074-82-4 potassium phtalimide 
• 75-26-3 isopropyl bromide 
• 78-77-3 Isobutyl bromide 
• 20320-33-6 2-(isopropylcarbamoyl)benzoic acid 
• 524-38-9 N-hydroxyphthalimide 
• 1914-20-1 N-methoxyphthalimide 
• 17858-14-9 dimethyl (1-chloro-1,3-dihydro-3-oxo-1-isobenzofuranyl)phosphonate 
• 136918-14-4 phthalimide 
• 67-63-0 isopropyl alcohol 
• 75-30-9 2-iodo-propane 
• 88-95-9 Phthaloyl dichloride 

Downstream Products

• 75-31-0 isopropylamine 
• 32003-14-8 4-benzyl-2H-phthalazin-1-one 
• 1265964-66-6 2-isopropyl-1-phenyisoindole 
• 1265964-63-3 2-isopropyl-1,3-diphenyisoindole 
• 55023-86-4 2-Isopropyl-2H-isoindol 
• 65399-00-0 2,3-dihydro-2-(1-methylethyl)-1H-isoindol-1-one 
• 5440-69-7 N-isopropylbenzamide 

Relevant articles and documents

Wavelength dependent photoextrusion and tandem photo-extrusion reactions of ninhydrin bis-acetals for the synthesis of 8-ring lactones, benzocyclobutenes and orthoanhydrides

Ninhydrin bis-acetals give access to 8-ring lactones, benzocyclo-butenes and spirocyclic orthoanhydrides through photoextrusion and tandem photoextrusion reactions. Syntheses of fimbricalyxlactone B, isoshihunine and numerous biologically-relevant heteroc

PPh3/I2/HCOOH: An efficient CO source for the synthesis of phthalimides

A straightforward and general method has been developed for the synthesis of phthalimide derivatives from 2-iodobenzamides and PPh3/I2/HCOOH in the presence of a catalytic amount of Pd(OAc)2. The reaction results demonstrate that PPh3/I2/HCOOH is a facile, efficient and safe CO source. The whole process is carried out in toluene at 80 °C and furnishes the desired products in good to excellent yields.

Method for synthesizing N-isopropylphthalimide

The invention discloses a method for synthesizing N-isopropylphthalimide. Phthalimide and propylene used as main reaction substrates undergo a nucleophilic addition reaction under the catalysis of a catalyst at a reaction temperature of 50-200 DEG C for 1-30 h to obtain the N-isopropylphthalimide, wherein a molar ratio of phthalimide to propylene in the reaction system is 1:1 to 1:10. The phthalimide and propylene used in the method are all cheap and easily-available raw materials, and the method also has the advantages of mild reaction conditions, no byproducts in the process, high conversionrate and low production cost. The content of normal bodies can reach 98% or more.