304015-28-9

Basic information

• Product Name: methyl 2-(2-{[tert-butyl(dimethyl)silyl]oxy}ethoxy)-4-nitrobenzoate
• Synonyms: methyl 2-(2-{[tert-butyl(dimethyl)silyl]oxy}ethoxy)-4-nitrobenzoate
• CAS NO: 304015-28-9
• Molecular Weight: 355.463
• Mol File: 304015-28-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 2-(2-{[tert-butyl(dimethyl)silyl]oxy}ethoxy)-4-nitrobenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-(2-{[tert-butyl(dimethyl)silyl]oxy}ethoxy)-4-nitrobenzoate(304015-28-9)
• EPA Substance Registry System: methyl 2-(2-{[tert-butyl(dimethyl)silyl]oxy}ethoxy)-4-nitrobenzoate(304015-28-9)

Safety Data

• Hazardous Substances Data: 304015-28-9(Hazardous Substances Data)

Upstream product

• 13684-28-1 2-hydroxy-4-nitro-benzoic acid methyl ester 
• 86864-60-0 2-(tert-butyldimethylsilyloxy)ethyl bromide 

Downstream Products

• 304015-30-3 2-(2-{[tert-butyl(dimethyl)silyl]oxy}ethoxy)-4-nitrobenzyl 1-(chloromethyl)-3-[(5,6,7-trimethoxy-1H-indol-2-yl)carbonyl]-2,3-dihydro-1H-benzo[e]indol-5-ylcarbamate 
• 304015-29-0 [2-(2-{[tert-butyl(dimethyl)silyl]oxy}ethoxy)-4-nitrophenyl]methanol 

Relevant articles and documents

Structure-activity relationships for 4-nitrobenzyl carbamates of 5-aminobenz[e]indoline minor groove alkylating agents as prodrugs for GDEPT in conjunction with E. coli nitroreductase

Twelve substituted 4-nitrobenzyl carbamate prodrugs of the 5-aminobenz[e]indoline class of DNA minor groove alkylating agents were prepared and tested as prodrugs for gene-directed enzyme prodrug therapy (GDEPT) using a two-electron nitroreductase (NTR) f