304863-14-7Relevant articles and documents
Cyclopropane-containing polyamine analogues are efficient growth inhibitors of a human prostate tumor xenograft in nude mice
Frydman, Benjamin,Blokhin, Andrei V.,Brummel, Sara,Wilding, George,Maxuitenko, Yulia,Sarkar, Aparajita,Bhattacharya, Subhra,Church, Dawn,Reddy, Venodhar K.,Kink, John A.,Marton, Laurence J.,Valasinas, Aldonia,Basu, Hirak S.
, p. 4586 - 4600 (2007/10/03)
Polyamine analogues 7, 10, 18, 27, and 32 containing cyclopropane rings were obtained by chemical synthesis. Their antineoplastic activities were assessed against the cultured human prostate tumor cell lines DU-145, DuPro, and PC-3. Decamines 32 and 27 ex