305-62-4

Basic information

• Product Name: 2,4-DIAMINO-BUTYRIC ACID
• Synonyms: DL-2,4-DIAMINO-N-BUTYRIC ACID;2,4-DIAMINO-BUTYRIC ACID;RARECHEM AK ZA 0003;2,4-diamino-butanoicaci;2,4-diaminobutanoicacid;alpha,gamma-diaminobutyricacid;R,S-2,4-DIAMINOBUTYRIC ACID;α,γ-Diaminobutyric acid
• CAS NO: 305-62-4
• Molecular Formula: C₄H₁₀N₂O₂
• Molecular Weight: 118.13
• EINECS: 206-166-2
• Product Categories: pharmacetical
• Mol File: 305-62-4.mol
• Article Data: 11

Chemical Properties

• Melting Point: 144 °C
• Boiling Point: 220.67°C (rough estimate)
• Appearance: /
• Density: 1.2188 (rough estimate)
• Refractive Index: 1.4386 (estimate)
• Storage Temp.: 2-8°C
• PKA: 1.85, 8.24, 10.44(at 25℃)
• CAS DataBase Reference: 2,4-DIAMINO-BUTYRIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-DIAMINO-BUTYRIC ACID(305-62-4)
• EPA Substance Registry System: 2,4-DIAMINO-BUTYRIC ACID(305-62-4)

Safety Data

• Hazardous Substances Data: 305-62-4(Hazardous Substances Data)

Usage

Description

2,4-Diaminobutyric acid, also known as DAB, is a diamino acid derived from butyric acid, where a hydrogen at position 2 and a hydrogen at position 4 are replaced by amino groups. It is a versatile compound with various applications in different industries due to its unique chemical structure and properties.

Uses

Used in Pharmaceutical Industry:
2,4-Diaminobutyric acid is used as a starting material for the synthesis of various pharmaceutical compounds. Its unique structure allows for the development of new drugs with potential therapeutic applications.
Used in Chemical Synthesis:
In the chemical industry, 2,4-diaminobutyric acid serves as a key building block for the creation of complex organic molecules. Its ability to form amide and peptide bonds makes it a valuable component in the synthesis of various chemical products.
Used in Research and Development:
2,4-Diaminobutyric acid is utilized in research and development for studying the properties and behavior of diamino acids. It can be used to investigate the effects of structural modifications on the biological activity and chemical reactivity of related compounds.
Used in Biochemical Applications:
In the field of biochemistry, 2,4-diaminobutyric acid can be employed as a component in the study of enzyme mechanisms, protein structure, and function. Its unique structure may provide insights into the role of diamino acids in biological systems.
Used in Material Science:
2,4-Diaminobutyric acid can be used in the development of novel materials with specific properties, such as conductivity, strength, or biocompatibility. Its ability to form complex structures and interact with other molecules makes it a promising candidate for material science applications.

InChI:InChI=1/C4H10N2O2/c5-2-1-3(6)4(7)8/h3H,1-2,5-6H2,(H,7,8)

Upstream product

• 4756-09-6 propane-1,1,3-tricarboxylic acid 
• 2483-65-0 3-amino-pyrrolidin-2-one 
• 102554-90-5 Pht-D/L-Dab(Pht)-OH 
• 13591-06-5 3-thioxo-tetrahydro-pyrrolo[1,2-c]imidazole-1,5-dione 
• 149010-54-8 2-Amino-4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-butyric acid methyl ester 
• 91861-97-1 2-Acetylamino-4-amino-N,N-diethyl-butyramide; hydrochloride 
• 85701-37-7 benzoylglycyl-N^γ-(pivaloyloxy)glutamine N-methylamide 
• 81546-73-8 dicyclohexylammonium N^α-benzyloxycarbonylamino-γ-nitrobutyrate 
• 87411-95-8 C₅₄H₅₄Cl₂N₈O₁₇ 
• 113719-16-7 <2,6-bis(1,1-dimethylethyl)-4-methoxyphenyl>-2,4-bis(acetamido)butanoat 
• 77287-34-4 formamide 

Downstream Products

• 87394-05-6 2,4-bis-benzoylamino-butyric acid 
• 70548-52-6 N,N'-dibenzoyl methyl ester 
• 115511-05-2 2-Amino-4-((S)-2-{(3S,4S)-4-[(S)-2-((S)-2-tert-butoxycarbonylamino-3-phenyl-propionylamino)-3-(3H-imidazol-4-yl)-propionylamino]-3-hydroxy-6-methyl-heptanoylamino}-4-methyl-pentanoylamino)-butyric acid 
• 1518-62-3 2,4-dihydroxybutanoic acid 
• 56-40-6 glycine 
• 617-45-8 aspartic Acid 
• 107-95-9 3-amino propanoic acid 
• 2130-77-0 2-Amino-4-benzyloxycarbonylamino-butyric acid 
• 2483-65-0 3-amino-pyrrolidin-2-one 

Relevant articles and documents

Immunomodulatory peptides

The invention relates to peptides derivatized with a hydrophilic polymer which, in some embodiments, bind to human FcRn and inhibit binding of the Fc portion of an IgG to an FcRn, thereby modulating serum IgG levels. The disclosed compositions and methods may be used in some embodiments, for example, in treating autoimmune diseases and inflammatory disorders. The invention also relates, in further embodiments, to methods of using and methods of making the peptides of the invention.

Hydrogels from biopolymers

Methods are disclosed for preparing linear or/and partial precross-linked poly-g-glutamic acid nanoparticle products, their reaction with compounds which contain vinyl groups, and the polymerization by chemical initiation or photopolymerization of these by light of predetermined wavelength. The final products of the present invention are useful as local drug delivery systems, dental surgery, and for inhibition of post-surgical adhesion. The hydrogels made from the biopolymers of the present invention may also be used in controlled release devices, superabsorbent materials and biomaterials like enzyme immobilization.

Peptides with an insulin-like action

Peptides with an insulin-like action, of formula I: STR1 in which G is a hydrogen atom, an amino add residue, or a monosubstituted or polysubstituted amino acid; D is an amino acid residue, a phosphoamino acid residue, a monosaccharide residue, or a covalent bond; E is --NH--(CH2)n --NR52, a glycerol residue, or --NH--(CH2)p --R6 --R7 ; R1 is (C1 -C4)-alkyl or =O; R2 is a sulfhydryl protecting group, (C1 -C3)-alkyl, or a hydrogen atom; R3 and R4, independently of one another, are a hydrogen atom or methyl; R5, each being identical or different, is a hydrogen atom, 1 to 6 monosaccharide residues, or 1 to 6 monosubstituted or polysubstituted monosaccharide residues; R6 is O PO4 H, PO2 H, NHCOO, S or OCOO; R7 is a hydrogen atom, 1 to 6 monosaccharide residues, or 1 to 6 monosubstituted or polysubstituted monosaccharide residues; w is an integer 1 or 2; their preparation and use for treatment of diabetes mellitus or insulin-independent diabetes.