305346-88-7

Basic information

• Product Name: 1H-Benzimidazole,1-(2-methylpropyl)-(9CI)
• Synonyms: 1H-Benzimidazole,1-(2-methylpropyl)-(9CI)
• CAS NO: 305346-88-7
• Molecular Formula: C₁₁H₁₄N₂
• Molecular Weight: 174.246
• Product Categories: BENZIMIDAZOLE
• Mol File: 305346-88-7.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 289.8±23.0 °C(Predicted)
• Appearance: /
• Density: 1.04±0.1 g/cm3(Predicted)
• PKA: 5.43±0.10(Predicted)
• CAS DataBase Reference: 1H-Benzimidazole,1-(2-methylpropyl)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Benzimidazole,1-(2-methylpropyl)-(9CI)(305346-88-7)
• EPA Substance Registry System: 1H-Benzimidazole,1-(2-methylpropyl)-(9CI)(305346-88-7)

Safety Data

• Hazardous Substances Data: 305346-88-7(Hazardous Substances Data)

Usage

Derivative of benzimidazole

Yes

Bicyclic aromatic compound

Yes

Class of compounds

Proton pump inhibitors (PPIs)

Commonly used to treat

Gastroesophageal reflux disease (GERD), peptic ulcers, Zollinger-Ellison syndrome

Mechanism of action

Reduces production of stomach acid

Provides relief from

Symptoms associated with excessive acid in the stomach

Side effects

Generally well-tolerated with few side effects when used as directed

Upstream product

• 51-17-2 benzoimidazole 
• 78-77-3 Isobutyl bromide 
• 120-72-9 indole 

Relevant articles and documents

N-Heterocyclic carbene-palladium-PEPPSI complexes and their catalytic activity in the direct C-H bond activation of heteroarene derivatives with aryl bromides: synthesis, and antimicrobial and antioxidant activities

In this study, a series of unsymmetrical 1,3-disubstituted benzimidazolium chlorides 2a-g with two nitrogen atoms substituted by different alkyl groups were synthesized in high yields as N-heterocyclic carbene (NHC) precursors. These benzimidazolium salts

KF/Al2O3-mediated N-alkylation of amines and nitrogen heterocycles and S-alkylation of thiols

KF/Al2O3 efficiently catalyzes N-alkylation of heterocyclic, primary, and secondary amines and S-alkylation of thiols with a variety of alkyl halides. The N-alkylation and S-alkylation adducts were produced in good to excellent yields and in short times. Copyright Taylor & Francis Group, LLC.