305370-83-6 Usage
Type of compound
Heterocyclic compound
Potential applications
Pharmaceutical, particularly in antimicrobial and antifungal agents
Studied for
Treatment of various infections, including bacterial and fungal infections
Unique feature
Chemical structure and properties make it a promising candidate for further research and development in medicinal chemistry
Subject of interest
Synthesis and characterization due to potential pharmacological significance
Check Digit Verification of cas no
The CAS Registry Mumber 305370-83-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,0,5,3,7 and 0 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 305370-83:
(8*3)+(7*0)+(6*5)+(5*3)+(4*7)+(3*0)+(2*8)+(1*3)=116
116 % 10 = 6
So 305370-83-6 is a valid CAS Registry Number.
305370-83-6Relevant articles and documents
Syntheses and EGFR kinase inhibitory activity of 6-substituted-4-anilino [1,7] and [1,8] naphthyridine-3-carbonitriles
Wissner, Allan,Hamann, Philip R.,Nilakantan, Ramaswamy,Greenberger, Lee M.,Ye, Fei,Rapuano, Timothy A.,Loganzo, Frank
, p. 1411 - 1416 (2007/10/03)
The syntheses and EGFR kinase inhibitory activity of a series of 6-substituted-4-anilino [1,7] and [1,8] naphthyridine-3-carbonitriles are described. Both reversible and irreversible binding inhibitors were prepared. These series were compared with each other and with the corresponding 4-anilinoquinoline-3-carbonitriles. Compounds having a 1,7-naphthyridine core structure can retain high potency while those with a 1,8-naphthyridine core are significantly less active. These results are consistent with molecular modeling observations.
