30565-51-6

Basic information

• Product Name: α-hydroxy-(4-chlorophenyl)acetic acid isopropyl ester
• Synonyms: α-hydroxy-(4-chlorophenyl)acetic acid isopropyl ester
• CAS NO: 30565-51-6
• Molecular Weight: 228.675
• Mol File: 30565-51-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: α-hydroxy-(4-chlorophenyl)acetic acid isopropyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: α-hydroxy-(4-chlorophenyl)acetic acid isopropyl ester(30565-51-6)
• EPA Substance Registry System: α-hydroxy-(4-chlorophenyl)acetic acid isopropyl ester(30565-51-6)

Safety Data

• Hazardous Substances Data: 30565-51-6(Hazardous Substances Data)

Upstream product

• 4998-15-6 4-chlorophenylglyoxal 
• 67-63-0 isopropyl alcohol 
• 7099-88-9 4-chlorophenylglyoxylic acid 
• 30565-44-7 isopropyl 2-(4-chlorophenyl)-2-oxoacetate 
• 34966-48-8 ethyl 2-(4-chlorophenyl)-2-oxoacetate 
• 4996-21-8 1-(4-chloro-phenyl)-2,2-dihydroxy-ethanone 

Downstream Products

• 30565-44-7 isopropyl 2-(4-chlorophenyl)-2-oxoacetate 
• 103807-49-4 Bromo-(4-chloro-phenyl)-acetic acid isopropyl ester 

Relevant articles and documents

Efficient Lewis acid catalyzed intramolecular Cannizzaro reaction

-

Ytterbium triflate-promoted tandem one-pot oxidation-cannizzaro reaction of aryl methyl ketones

(Chemical Equation Presented) Ytterbium triflate was shown to be an effective catalyst in promoting the synthesis of either isopropyl esters or free α-hydroxy-arylacetic acids from substituted aromatic glyoxals and aryl methyl ketones, respectively. The reaction to provide acids starting from differently substituted ketones was carried out by an environmentally friendly method using an aqueous medium as a solvent and giving the adducts in 78-99% yield without any further purification after the usual workup.

Catalysis by Cobalt Schiff's Base Complexes in Highly Selective Conversion of Arylglyoxals to α-Aryl-α-hydroxyacetic Esters

Cobalt Schiff's base complexes catalyse highly selective conversion of arylglyoxals to α-aryl-α-hydroxyacetic esters in alcohols; Lewis acidity of CoIII species may be responsible to the catalysis.