30566-92-8 Usage
Description
5-(N,N-Dibenzylglycyl)salicylamide is an organic compound with the chemical properties of a light beige powder. It is a derivative of salicylic acid, featuring a dibenzylglycyl group attached to the salicylic amide structure. 5-(N,N-Dibenzylglycyl)salicylamide is known for its potential applications in the pharmaceutical industry, particularly as an intermediate in the synthesis of certain drugs.
Uses
Used in Pharmaceutical Industry:
5-(N,N-Dibenzylglycyl)salicylamide is used as an intermediate in the synthesis of labetalol, a medication used for the treatment of high blood pressure. Its role in the production process is crucial, as it helps in the formation of the final drug product.
As an intermediate compound, 5-(N,N-Dibenzylglycyl)salicylamide plays a significant role in the development and manufacturing of labetalol, which is an essential drug for managing hypertension. Its chemical properties and structure make it a valuable component in the pharmaceutical industry, contributing to the creation of effective medications for various health conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 30566-92-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,0,5,6 and 6 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 30566-92:
(7*3)+(6*0)+(5*5)+(4*6)+(3*6)+(2*9)+(1*2)=108
108 % 10 = 8
So 30566-92-8 is a valid CAS Registry Number.
InChI:InChI=1/C23H22N2O3/c24-23(28)20-13-19(11-12-21(20)26)22(27)16-25(14-17-7-3-1-4-8-17)15-18-9-5-2-6-10-18/h1-13,26H,14-16H2,(H2,24,28)/p+1
30566-92-8Relevant articles and documents
Synthetic method of 5-N,N-dibenzylamine acetyl salicylamide
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, (2019/03/08)
The invention discloses a synthetic method of 5-N,N-dibenzylamine acetyl salicylamide. The synthetic method comprises the steps of protecting salicylamide with aldehyde, ketone or acetal and ketal with different substituents, reacting with an alpha-halogenated acylation reagent so as to obtain an intermediate II, substituting halogen atoms with dibenzylamine, and finally carrying out acidificationdeprotection, so as to obtain 5-N,N-dibenzylamine acetyl salicylamide. The synthetic method provided by the invention has the characteristics of high yield, few impurities, low cost, easiness in amplification and the like.
Arylethanolamines derived from salicylamide with α- and β-adrenoceptor blocking activities. Preparation of labetalol, its enantiomers, and related salicylamides
Clifton,Collins,Hallett,Hartley,Lunts,Wicks
, p. 670 - 679 (2007/10/02)
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