305806-98-8

Basic information

• Product Name: Acetamide, N-[(2R,4S)-1-benzoyl-1,2,3,4-tetrahydro-2-methyl-4-quinolinyl]-N-phenyl -, rel-
• CAS NO: 305806-98-8
• Molecular Formula: C25H24N2O2
• Molecular Weight: 384.478
• Mol File: 305806-98-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Acetamide, N-[(2R,4S)-1-benzoyl-1,2,3,4-tetrahydro-2-methyl-4-quinolinyl]-N-phenyl -, rel-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, N-[(2R,4S)-1-benzoyl-1,2,3,4-tetrahydro-2-methyl-4-quinolinyl]-N-phenyl -, rel-(305806-98-8)
• EPA Substance Registry System: Acetamide, N-[(2R,4S)-1-benzoyl-1,2,3,4-tetrahydro-2-methyl-4-quinolinyl]-N-phenyl -, rel-(305806-98-8)

Safety Data

• Hazardous Substances Data: 305806-98-8(Hazardous Substances Data)

Upstream product

• 98-88-4 benzoyl chloride 
• 857-45-4 (+/-)-4c-anilino-1-benzoyl-2r-methyl-1,2,3,4-tetrahydro-quinoline 
• 75-36-5 acetyl chloride 
• 857-45-4 (+/-)-4t-anilino-1-benzoyl-2r-methyl-1,2,3,4-tetrahydro-quinoline 
• 506-96-7 Acetyl bromide 
• 1202402-21-8 C₂₃H₂₂N₂O 

Relevant articles and documents

Tetrahydroquinoline derivatives as CRTH2 antagonists

A series of tetrahydroquinoline-derived inhibitors of the CRTH2 receptor was discovered by a high throughput screen. Optimization of these compounds for potency and pharmacokinetic properties led to the discovery of potent and orally bioavailable CRTH2 an

Tetrahydroquinoline derivatives as CRTH2 antagonists

The invention relates to compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, R7 and R8 are as defined in the description, their use as medicament, pharmaceutical compositions containing them and processes for their preparation.