305819-43-6

Basic information

• Product Name: methyl N-benzoyl-β-phenylphenylalaninate
• Synonyms: methyl N-benzoyl-β-phenylphenylalaninate
• CAS NO: 305819-43-6
• Molecular Weight: 359.425
• Mol File: 305819-43-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: methyl N-benzoyl-β-phenylphenylalaninate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl N-benzoyl-β-phenylphenylalaninate(305819-43-6)
• EPA Substance Registry System: methyl N-benzoyl-β-phenylphenylalaninate(305819-43-6)

Safety Data

• Hazardous Substances Data: 305819-43-6(Hazardous Substances Data)

Upstream product

• 139517-52-5 2-phenyl-4-(diphenylmethylene)-5(4H)-1,3-oxazolone 
• 526214-83-5 methyl 2-benzamido-3,3-diphenylpropenoate 
• 101-81-5 Diphenylmethane 
• 1205-08-9 methyl hippurate 
• 1013-88-3 Benzophenone imine 
• 495-69-2 Hippuric Acid 

Downstream Products

• 915750-90-2 benzyl 2-(N-tert-butoxycarbonylamino)-3,3-diphenylpropanoate 
• 119363-63-2 2-(N-tert-butoxycarbonylamino)-3,3-diphenylpropanoic acid 
• 119273-60-8 2-amino-3,3-diphenylpropanoic acid hydrochloride 

Relevant articles and documents

Synthesis of enantiomerically pure β,β-diphenylalanine (Dip) and fluorenylglycine (Flg)

A new strategy for the preparation of both enantiomers of two phenylalanine analogues, β,β-diphenylalanine and fluorenylglycine, has been developed. The combination of a high yielding racemic synthesis and a very efficient resolution procedure has provided significant amounts of each amino acid in enantiomerically pure form and suitably protected for use in peptide synthesis. This methodology can be easily applied to the preparation of larger quantities of enantiopure compounds.

Photochemical alkylation of glycine leading to phenylalanines

UV photolysis of protected glycines in the presence of di-tert-butyl peroxide, benzophenone and substituted toluenes is shown to lead to selective alkylation at the α-position. Phenylalanines are isolated in yields of generally > 50% (based on recovered s