306-12-7 Usage
Description
Oxophenarsine, also known as Mapharsen, is an organoarsenic compound with potential pharmaceutical applications. It is characterized by its ability to interact with certain biological targets, making it a candidate for various therapeutic uses.
Uses
Used in Pharmaceutical Industry:
Oxophenarsine is used as a therapeutic agent for the treatment of certain diseases, particularly those involving the nervous system. Its mechanism of action involves targeting specific biological pathways, which can help in managing the symptoms and progression of the disease.
Used in Chemical Industry:
In the chemical industry, oxophenarsine may be used as a catalyst or in the development of new chemical processes. Its unique properties could potentially enhance the efficiency and selectivity of certain reactions, leading to improved industrial applications.
Safety Profile
Poison by ingestion and intravenous routes. When heated to decomposition it emits toxic fumes of NOx and As
Enzyme inhibitor
This sulfhydryl-reactive arsenical (FW = 199.04 g/mol; CAS 306-12-7), variously named Mapharsen, Ehrlich-5, oxyphenarsine, oxarsan, arsinoxide, 3-amino-4-hydroxybenzenearsenoxide, and 2-amino-4-arsenosophenol, was originally developed by Nobelist Paul Ehrlich as an anti-syphilis drug. (Note: do not confuse this compound with oxophenylarsine, also known phenylarsine oxide). It is now used as an antiprotozomal agent, particularly against Trypanosoma. Oxophenarsine is typically supplied as the hydrochloride (FW = 235.50 g/mol) and is readily soluble in water. (See also Dichlorophenarsine) Target(s): acetyl-CoA acyltransferase; actomyosin ATPase; aldehyde dehydrogenase; alkaline phosphatase; asparagine synthetase; ATPase, rat brain; ATPase, trypanosomal; cathepsin; cholinesterase; deoxyribonuclease; diisopropylfluorophosphatase; γ-glutamyl hydrolase, or pteroylglutamate conjugase; glyceraldehyde-3-phosphate dehydrogenase; a-glycerophosphate oxidase; hexokinase; myosin ATPase; pyrophosphatase; pyruvate decarboxylase; pyruvate oxidase; ribose-5-phosphate isomerase; succinate dehydrogenase; succinate oxidase; urease.
Check Digit Verification of cas no
The CAS Registry Mumber 306-12-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,0 and 6 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 306-12:
(5*3)+(4*0)+(3*6)+(2*1)+(1*2)=37
37 % 10 = 7
So 306-12-7 is a valid CAS Registry Number.
InChI:InChI=1/C6H6AsNO2/c8-5-3-4(7-10)1-2-6(5)9/h1-3,9H,8H2
