3061-95-8

Basic information

• Product Name: H-D-ALA-PHE-OH
• Synonyms: H-D-ALA-PHE-OH;2-(2-aminopropanoylamino)-3-phenylpropanoic acid;2-(2-azanylpropanoylamino)-3-phenyl-propanoic acid;2-(alanylamino)-3-phenyl-propionic acid;D-Ala-Phe-OH≥ 98% (TLC)
• CAS NO: 3061-95-8
• Molecular Formula: C₁₂H₁₆N₂O₃
• Molecular Weight: 236.27
• Mol File: 3061-95-8.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 487.6°Cat760mmHg
• Flash Point: 248.7°C
• Appearance: /
• Density: 1.222g/cm³
• Refractive Index: 1.565
• Storage Temp.: -15°C
• CAS DataBase Reference: H-D-ALA-PHE-OH(CAS DataBase Reference)
• NIST Chemistry Reference: H-D-ALA-PHE-OH(3061-95-8)
• EPA Substance Registry System: H-D-ALA-PHE-OH(3061-95-8)

Safety Data

• Hazardous Substances Data: 3061-95-8(Hazardous Substances Data)

Usage

General Description

H-D-ALA-PHE-OH, also known as D-alanyl-phenylalanine, is a chemical compound that belongs to the class of organic compounds known as dipeptides. It is a dipeptide consisting of two amino acids, alanine and phenylalanine, linked by a peptide bond. The "D" refers to the configuration of the alanine amino acid, indicating it is in the D (Dextro) conformation -- the opposite of the typical L (Levo) conformation found in naturally occurring proteins. The "OH" signifies the presence of a hydroxyl group. H-D-ALA-PHE-OH is used in scientific and biochemical research, such as peptide synthesis, and can have specific bioactivity depending on their structure. In general, dipeptides like H-D-ALA-PHE-OH are known for their potential therapeutic applications, such as antiviral, antimicrobial, or antitumor activity.

InChI:InChI=1/C12H16N2O3/c1-8(13)11(15)14-10(12(16)17)7-9-5-3-2-4-6-9/h2-6,8,10H,7,13H2,1H3,(H,14,15)(H,16,17)/t8-,10?/m1/s1

Upstream product

• 94883-19-9 D-(N-tert-butoxycarbonylalanyl)-L-phenylalanine 
• 100431-46-7 N-<(S)-2-(aminocarbonyl)-1-oxopropyl>-L-phenyl alanine 
• 16874-17-2 L-phenylalanine tert-butyl ester 
• 100431-52-5 N-<(R,S)-2-carboxy-1-oxopropyl>-L-phenyl alanine tert-butyl ester 
• 100431-53-6 N-<(R,S)-2-(aminocarbonyl)-1-oxopropyl>-L-phenyl alanine tert-butyl ester 
• 100431-51-4 N-<(R,S)-2-(ethoxycarbonyl)-1-oxopropyl>-L-phenyl alanine tert-butyl ester 
• 63-91-2 L-phenylalanine 

Downstream Products

• 147424-35-9 Z-Tyr-D-Ala-Phe-OH 
• 94849-38-4 Boc-Tyr-D-Ala-Phe-OH 
• 132125-59-8 H-Tyr-D-Ala-Phe-Val-Val-Asp-Gly-NH₂ 
• 132125-58-7 H-Tyr-D-Ala-Phe-Val-Asp-Val-Gly-NH₂ 
• 132103-70-9 H-Tyr-D-Ala-Phe-Asp-Val-Val-Gly-OH 
• 122752-15-2 deltorphin C 
• 131152-66-4 H-Tyr-D-Ala-Phe-Gly-Val-Val-Asp-NH₂ 
• 1025941-24-5 (S)-3-((S)-2-{(R)-2-[(S)-2-tert-Butoxycarbonylamino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-N-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid tert-butyl ester 
• 1027166-82-0 ((S)-2-{(S)-2-[(S)-2-((S)-2-{(R)-2-[(S)-2-tert-Butoxycarbonylamino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-3-carbamoyl-propionylamino]-3-methyl-butyrylamino}-3-methyl-butyrylamino)-acetic acid ethyl ester 
• 1025956-29-9 C₄₆H₆₈N₈O₁₂ 
• 1026283-37-3 (S)-3-((S)-2-{(R)-2-[(S)-2-tert-Butoxycarbonylamino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-N-{[(S)-1-((S)-1-carbamoyl-2-methyl-propylcarbamoyl)-2-methyl-propylcarbamoyl]-methyl}-succinamic acid tert-butyl ester 
• 1027906-73-5 C₄₈H₇₁N₇O₁₃ 

Relevant articles and documents

Unique sequence in deltorphin C confers structural requirement for δ opioid receptor selectivity

A series of deltorphin C (H-Tyr-D-Ala-Phe-Asp-Val-Val-Gly-NH2) analogues were synthesized to assess the consequences of changing anionic and hydrophobic residues on δ receptor selectivity.Analogues with altered C-terminal groups, inverted sequences, or es