306298-82-8

Basic information

• Product Name: 4H-1,2,4-triazole-3-thiol, 5-(3-fluorophenyl)-
• Synonyms: 4H-1,2,4-triazole-3-thiol, 5-(3-fluorophenyl)-;5-(3-fluorophenyl)-4H-1,2,4-triazole-3-thiol;5-(3-fluorophenyl)-1,2-dihydro-1,2,4-triazole-3-thione
• CAS NO: 306298-82-8
• Molecular Formula: C₈H₆FN₃S
• Molecular Weight: 195.2167432
• Mol File: 306298-82-8.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4H-1,2,4-triazole-3-thiol, 5-(3-fluorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-1,2,4-triazole-3-thiol, 5-(3-fluorophenyl)-(306298-82-8)
• EPA Substance Registry System: 4H-1,2,4-triazole-3-thiol, 5-(3-fluorophenyl)-(306298-82-8)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 306298-82-8(Hazardous Substances Data)

Upstream product

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Relevant articles and documents

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The invention belongs to the technical field of medicines, and relates to a dammarane sapogenin derivative and a preparation method and application thereof. A series of dammarane sapogenin derivativesare obtained by combining dammarane sapogenins from plants with different groups. Anticancer activity evaluation and anticancer activity mechanism research are carried out on the derivative, and results show that the prepared dammarane sapogenin derivative has a remarkable anticancer effect, has no toxic effect on normal cells and can be used for preparing drugs for treating cancers.

Fluorine containing heterocyclic compounds: Synthesis of 6-substituted-2-substituted-aryl-1,2,4-triazolo[5,1-b] 1,3,5-thiadiazin-7-one derivatives

A group of heterocylic compounds of condensed triazole-thiadiazinone derivatives containing fluorine (IIIa-h) were obtained in good yields by the reactions of the corresponding 3-aryl-5-mercapto-1,2,4-triazole (IIa-d) with N-substituted-N-chloromethyl carbamoyl chloride (I) in the presence of potassium carbonate in N,N-dimethylformamide at room temperature. Cyclization of 3-(2,3,5-trifluoro-4-methoxyl)phenyl-5-mercapto-1,2,4-triazole (IIe) with I was difficult due to an intermolecular hydrogen bond of IIe. The structures of the compounds synthesized were confirmed by IR, MS, 1H NMR and elemental analyses. Fungicidal and insecticidal activities of these compounds were also studied.