3063-71-6 Usage
Description
Cytosine 5′-monophosphate N-acetylneuraminic acid (CMP-Neu5Ac), also known as CYTIDINE 5'-MONOPHOSPHO-N-, is a sugar-nucleotide that is produced by CMP-Neu5Ac synthetase from CTP and Neu5Ac. It plays a crucial role in the biosynthesis of sialic acids, which are important components of various biological molecules, including glycoproteins and glycolipids.
Uses
1. Used in Research and Diagnostics:
CYTIDINE 5'-MONOPHOSPHO-Nis used as a standard in high-performance anion-exchange chromatography with pulsed amperometric detection (HPAEC-PAD) for nucleotide sugar analysis. This application is particularly relevant in the study of Joubert syndrome type 10 (JBTS10) patient cells and control skin fibroblasts, aiding in the understanding of the molecular basis of the disease and potential therapeutic strategies.
2. Used in Enzymatic Sialylation:
CYTIDINE 5'-MONOPHOSPHO-Nserves as a substrate for the enzymatic sialylation of G2 glycoforms, which is essential for the proper functioning of various biological processes. This application is crucial in the development of resialylation assays and in-vitro sialyltransferase assays, which are important tools for studying the role of sialic acids in cellular processes and their potential as therapeutic targets.
3. Used in Pharmaceutical and Biotechnology Industries:
CYTIDINE 5'-MONOPHOSPHO-Nmay also be used in the development of novel drug delivery systems and therapeutic strategies targeting sialic acid-related pathways. Its role in the biosynthesis of sialic acids makes it a valuable compound for research and development in the pharmaceutical and biotechnology industries, potentially leading to the discovery of new treatments for various diseases and conditions.
Biochem/physiol Actions
Cytidine-5′-monophospho-N-acetylneuraminic acid (CMP-Sialic acid) is a substrate for sialyltransferases. It is used for the enzymatic sialylation of glycans.
Check Digit Verification of cas no
The CAS Registry Mumber 3063-71-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,0,6 and 3 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 3063-71:
(6*3)+(5*0)+(4*6)+(3*3)+(2*7)+(1*1)=66
66 % 10 = 6
So 3063-71-6 is a valid CAS Registry Number.
