306934-85-0

Basic information

• Product Name: (2,5-DIMETHYL-3-FURYL)METHYLAMINE
• Synonyms: (2,5-DIMETHYL-3-FURYL)METHYLAMINE;BUTTPARK 95\50-60;3-(Aminomethyl)-2,5-dimethylfuran 90%;(2,5-Dimethyl-3-furyl)methylamine90%;(2,5-Dimethylfur-3-yl)methylamine;(2,5-diMethylfuran-3-yl)MethanaMine;3-(Aminomethyl)-2,5-dimethylfuran
• CAS NO: 306934-85-0
• Molecular Formula: C₇H₁₁NO
• Molecular Weight: 125.17
• Mol File: 306934-85-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 42-56°C/0.1mm
• Flash Point: 61.7°C
• Appearance: /
• Density: 1.003g/cm³
• Vapor Pressure: 0.993mmHg at 25°C
• Refractive Index: 1.499
• PKA: 9.14±0.29(Predicted)
• CAS DataBase Reference: (2,5-DIMETHYL-3-FURYL)METHYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: (2,5-DIMETHYL-3-FURYL)METHYLAMINE(306934-85-0)
• EPA Substance Registry System: (2,5-DIMETHYL-3-FURYL)METHYLAMINE(306934-85-0)

Safety Data

• Hazard Codes: C,Xn
• Statements: 36/37/38-36-22
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 306934-85-0(Hazardous Substances Data)

Usage

General Description

(2,5-DIMETHYL-3-FURYL)METHYLAMINE is a chemical compound with the molecular formula C8H11NO. It is also known by the synonym N-(2,5-dimethylfurfuryl)methylamine. (2,5-DIMETHYL-3-FURYL)METHYLAMINE is an amine, which means it contains a basic nitrogen atom. It is used in organic synthesis as a reagent for the formation of various chemical compounds. The presence of the furan ring makes it useful in the production of pharmaceuticals and agrochemicals. It is also used in the production of flavor and fragrance compounds, particularly those that have a fruity or floral aroma. Additionally, (2,5-DIMETHYL-3-FURYL)METHYLAMINE can be used as a building block in the synthesis of various fine chemicals and specialty materials.

InChI:InChI=1/C7H11NO/c1-5-3-7(4-8)6(2)9-5/h3H,4,8H2,1-2H3

Upstream product

• 636-44-2 2,5-dimethylfuran-3-carboxylic acid 
• 66806-31-3 2,5-dimethylfuran-3-carboxamide 

Relevant articles and documents

Design and synthesis of heteroaromatic-based benzenesulfonamide derivatives as potent inhibitors of H5N1 influenza A virus

Influenza A virus is an enveloped negative single-stranded RNA virus that causes febrile respiratory infection and represents a clinically challenging threat to human health and even lives worldwide. Even more alarming is the emergence of highly pathogenic avian influenza (HPAI) strains such as H5N1, which possess much higher mortality rate (60%) than seasonal influenza strains in human infection. In this study, a novel series of heteroaromatic-based benzenesulfonamide derivatives were identified as M2 proton channel inhibitors. A systematic investigation of the structure-activity relationships and a molecular docking study demonstrated that the sulfonamide moiety and 2,5-dimethyl-substituted thiophene as the core structure played significant roles in the anti-influenza activity. Among the derivatives, compound 11k exhibited excellent antiviral activity against H5N1 virus with an EC50 value of 0.47 μM and selectivity index of 119.9, which are comparable to those of the reference drug amantadine.