306935-77-3 Usage
Main properties
1. Chemical name: 4-(2,6-Diethylanilino)-4-oxobut-2-enoic acid
2. Common name: Lovastatin
3. Derived from a natural product found in certain fungi
4. Used as a medication to lower cholesterol and decrease the risk of heart disease
5. Inhibits the enzyme HMG-CoA reductase
6. Prescribed in combination with a healthy diet and exercise
Specific content
Compound derived from natural fungi product
Medication used to lower cholesterol and decrease risk of heart disease
Inhibits HMG-CoA reductase enzyme
Reduces cholesterol production in the liver
Prescribed in combination with a healthy diet and exercise for high cholesterol and lipid disorders treatment.
Check Digit Verification of cas no
The CAS Registry Mumber 306935-77-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,0,6,9,3 and 5 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 306935-77:
(8*3)+(7*0)+(6*6)+(5*9)+(4*3)+(3*5)+(2*7)+(1*7)=153
153 % 10 = 3
So 306935-77-3 is a valid CAS Registry Number.
InChI:InChI=1/C14H17NO3/c1-3-10-6-5-7-11(4-2)14(10)15-12(16)8-9-13(17)18/h5-9H,3-4H2,1-2H3,(H,15,16)(H,17,18)/b9-8+
306935-77-3Relevant articles and documents
Unusual regio- and stereo-selectivity in Diels-Alder reactions between bulky N-phenylmaleimides and anthracene derivatives
Chen, Hao,Yao, Erdong,Xu, Chi,Meng, Xiao,Ma, Yuguo
supporting information, p. 5102 - 5107 (2014/07/08)
Unusual regio- and stereo-selectivity in Diels-Alder (D-A) reactions were achieved between bulky N-phenylmaleimides and anthracene derivatives. Using multiple substituents with steric hindrance on both diene and dienophile, a noticeable shift toward 1,4-addition was successfully obtained. The substrate scope in this reaction was broad and the highest yield of anti-1,4-adducts was over 90%. Novel structures of anti-1,4-adducts were confirmed by single crystal X-ray diffraction analysis. This study not only provides the first reported method of synthesizing anti-1,4-adducts and achieving otherwise unattainable regio- and stereo-selectivity, but also elucidates the importance of combining the steric effects of two reactants to shift products toward 1,4-adducts. Moreover, the resulting 1,4-adducts could be further functionalized through their halogen groups via carbon-carbon coupling reactions.
