306936-81-2 Usage
General Description
ETHYL 2-[2,4-BIS(TRIFLUOROMETHYL)PHENYL]-2-OXOACETATE is a chemical compound with the molecular formula C13H8F12O4. It is a derivative of oxoacetic acid and contains two trifluoromethylphenyl groups. ETHYL 2-[2,4-BIS(TRIFLUOROMETHYL)PHENYL]-2-OXOACETATE is commonly used as a reagent in organic synthesis and pharmaceutical research. It is known for its high reactivity and ability to undergo various chemical transformations, making it a valuable building block for the synthesis of complex organic molecules. ETHYL 2-[2,4-BIS(TRIFLUOROMETHYL)PHENYL]-2-OXOACETATE has potential applications in the development of new drugs, agrochemicals, and other specialty chemicals. However, it should be handled with care due to its potential hazards and toxicity.
Check Digit Verification of cas no
The CAS Registry Mumber 306936-81-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,0,6,9,3 and 6 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 306936-81:
(8*3)+(7*0)+(6*6)+(5*9)+(4*3)+(3*6)+(2*8)+(1*1)=152
152 % 10 = 2
So 306936-81-2 is a valid CAS Registry Number.
InChI:InChI=1/C12H8F6O3/c1-2-21-10(20)9(19)7-4-3-6(11(13,14)15)5-8(7)12(16,17)18/h3-5H,2H2,1H3
306936-81-2Relevant articles and documents
The synthesis and structure-activity relationships of 1,3-diaryl 1,2,4-(4H)-triazol-5-ones: A new class of calcium-dependent, large conductance, potassium (maxi-K) channel openers targeted for urge urinary incontinence
Hewawasam, Piyasena,Erway, Matthew,Thalody, George,Weiner, Harvey,Boissard, Christopher G.,Gribkoff, Valentin K.,Meanwell, Nicholas A.,Lodge, Nicholas,Starrett, Jr, John E.
, p. 1117 - 1120 (2007/10/03)
A series of 1,3-diaryl 1,2,4-(4H)-triazol-5-ones was prepared and shown by electrophysiological analysis to activate a cloned maxi-K channel mSlo (or hSlo) expressed in Xenopus laevis oocytes. The effects of these structurally novel maxi-K channel openers on bladder contractile function were studied in vitro using isolated rat bladder strips pre-contracted with carbachol. Several 1,3-diaryl 1,2,4-(4H)-triazol-5-one derivatives were found to be potent smooth muscle relaxants but this activity did not completely correlate with maxi-K channel opening.
