306990-96-5

Basic information

• Product Name: 1H-1,2,3-benzotriazol-1-yl(4-diethylaminophenyl)-1,2-ethanedione
• Synonyms: 1H-1,2,3-benzotriazol-1-yl(4-diethylaminophenyl)-1,2-ethanedione
• CAS NO: 306990-96-5
• Molecular Weight: 294.356
• Mol File: 306990-96-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1H-1,2,3-benzotriazol-1-yl(4-diethylaminophenyl)-1,2-ethanedione(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-1,2,3-benzotriazol-1-yl(4-diethylaminophenyl)-1,2-ethanedione(306990-96-5)
• EPA Substance Registry System: 1H-1,2,3-benzotriazol-1-yl(4-diethylaminophenyl)-1,2-ethanedione(306990-96-5)

Safety Data

• Hazardous Substances Data: 306990-96-5(Hazardous Substances Data)

Upstream product

• 95-14-7 1,2,3-Benzotriazole 
• 5429-28-7 4-(diethylamino)benzoic acid 
• 37073-15-7 1-(methanesulfonyl)-1H-1,2,3-benzotriazole 

Downstream Products

• 95-14-7 1,2,3-Benzotriazole 
• 68289-19-0 1,2-bis(4-(diethylamino)phenyl)ethane-1,2-dione 
• 118024-66-1 4-(N,N-diethylamino)benzamide 

Relevant articles and documents

C-acylation of 2-methylfuran and thiophene using N-acylbenzotriazoles

Reactions of 2-methylfuran and thiophene with readily available N-acylbenzotriazoles (RCOBt, where R = 4-tolyl, 4-methoxyphenyl, benzyl, 4-nitrophenyl, 4-diethylaminophenyl, 2-pyridyl and 1-naphthyl) in the presence of TiCl4 or ZnBr2 produced 2-methyl-4-acylfurans 2a-e and 2-acylthiophenes 3a-f in average yields of 54 % and 75 %, respectively. Literature yields for the preparation of the same compounds are significantly lower.

N-acylbenzotriazoles: Neutral acylating reagents for the preparation of primary, secondary, and tertiary amides

Readily available N-acylbenzotriazoles 2a-q efficiently acylate aqueous ammonia and primary and secondary amines to give primary, secondary, and tertiary amides in good to excellent yields. The wide applicability of the procedure is illustrated by the preparation of (i) α-hydroxyamides from α-hydroxy acids and of (ii) perfluoroalkylated amides.