3070-86-8

Basic information

• Product Name: N,N'-(OXYDI-4,1-PHENYLENE)BISACETAMIDE
• Synonyms: N,N'-(OXYDI-4,1-PHENYLENE)BISACETAMIDE;44DIACETAMIDODIPHENYLETHER;Bis(p-acetylaminophenyl) Ether;N,N'-(oxybis(4,1-phenylene))diacetamide;Acetaminophen Impurity N
• CAS NO: 3070-86-8
• Molecular Formula: C₁₆H₁₆N₂O₃
• Molecular Weight: 284.31
• Mol File: 3070-86-8.mol
• Article Data: 5

Chemical Properties

• Melting Point: 230-231 °C(lit.)
• Boiling Point: 554.4°Cat760mmHg
• Flash Point: 289.1°C
• Appearance: /
• Density: 1.256g/cm³
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: DMSO (Slightly), Methanol (Slightly)
• PKA: 14.16±0.70(Predicted)
• CAS DataBase Reference: N,N'-(OXYDI-4,1-PHENYLENE)BISACETAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N,N'-(OXYDI-4,1-PHENYLENE)BISACETAMIDE(3070-86-8)
• EPA Substance Registry System: N,N'-(OXYDI-4,1-PHENYLENE)BISACETAMIDE(3070-86-8)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 3070-86-8(Hazardous Substances Data)

Usage

Description

N,N'-(OXYDI-4,1-PHENYLENE)BISACETAMIDE is a chemical compound with the molecular formula C16H16N2O3. It is a white crystalline solid and is known for its role in the synthesis of various chemical compounds and materials.

Uses

Used in Chemical Synthesis:
N,N'-(OXYDI-4,1-PHENYLENE)BISACETAMIDE is used as a chemical reagent for the synthesis of photosensitive polymer compounds. Its unique structure allows it to be a key component in the creation of materials with light-sensitive properties, which can be utilized in various applications such as optical devices and sensors.
Used in Optical Applications:
N,N'-(OXYDI-4,1-PHENYLENE)BISACETAMIDE is also used in the development of optical applications due to its photosensitive nature. N,N'-(OXYDI-4,1-PHENYLENE)BISACETAMIDE can be incorporated into materials that respond to light, making it a valuable asset in the field of optoelectronics and photonics.
Used in Pharmaceutical Industry:
N,N'-(OXYDI-4,1-PHENYLENE)BISACETAMIDE is used as a precursor in the preparation of benzimidazole derivatives. These derivatives have been found to exhibit anti-tumor activity through the induction of apoptosis, a process that leads to the programmed cell death of cancerous cells. This makes the compound a promising candidate for the development of new cancer treatments and therapies.

Upstream product

• 108-24-7 acetic anhydride 
• 101-80-4 4,4'-oxydiphenylene diamine 
• 64-19-7 acetic acid 
• 2687-41-4 N-[4-(4-aminophenoxy)phenyl]acetamide 
• 101-63-3 bis(4-nitrophenyl)ether 
• 2687-40-3 4-nitrophenyl 4'-acetamidophenyl ether 
• 103-90-2 4-acetaminophenol 
• 6149-33-3 4-(4-nitrophenoxy)aniline 
• 15267-98-8 sodium 4-aminophenolate 
• 100-00-5 4-chlorobenzonitrile 
• 824-78-2 4-nitrophenol sodium salt 
• 100-02-7 4-nitro-phenol 

Downstream Products

• 3070-87-9 N-[4-(4-acetylamino-3-nitrophenoxy)-2-nitrophenyl]acetamide 
• 3273-78-7 4-(4-amino-3-nitrophenoxy)-2-nitrophenylamine 
• 2676-59-7 bis(3,4-diaminophenyl)ether 
• 894734-47-5 5,5'-oxy-bis[2-(4'-methoxyphenyl)-1H-benzimidazole] 
• 1403460-70-7 5,5'-oxy-bis[2-(3',5'-dimethoxyphenyl)-1H-benzimidazole] 
• 1403460-71-8 5,5'-oxy-bis[2-(3',4',5'-trimethoxyphenyl)-1H-benzimidazole] 
• 1403460-72-9 5,5'-oxy-bis[2-(3'-methoxy-4'-hydroxyphenyl)-1H-benzimidazole] 
• 73672-91-0 2,2'-diphenyl-5,5'-bisbenzimidazolyl ether 
• 1403460-73-0 5,5'-oxy-bis[2-(4'-bromophenyl)-1H-benzimidazole] 
• 1403460-74-1 5,5'-oxy-bis[2-(2',4'-dichlorophenyl)-1H-benzimidazole] 
• 1403460-75-2 5,5'-oxy-bis[2-(4'-fluorophenyl)-1H-benzimidazole] 

Relevant articles and documents

Preparation method 3,3 '-dinitro -4, 4' - diacetyl diaminodiphenyl ether

The preparation method of 3, 3 ’ -dinitro -4 and 4 ’ -diacetyl diaminodiphenyl ether comprises the following steps of: adding an acylating agent to 4 and 4 ’ - diaminodiphenyl ether to carry out acylation reaction to obtain an acylation product. The nitra

Newly synthesized bis-benzimidazole derivatives exerting anti-tumor activity through induction of apoptosis and autophagy

In this study, a new series of bis-benzimidazole derivatives were designed and synthesized. Most of these new compounds showed significant anti-tumor activity in vitro compared to Hoechst 33258. Among them, the most potent compound 8 had the IC50/su

Synthesis and Anthelmintic Activity of 2-Substituted 5(6)-(5-Benzimidazolyloxy)- and 5(6)-Aryloxybenzimidazoles

A number of diaryl oxides (12-17 and 22-35) and 2,2'-disubstituted-5,5'-dibenzimidazolyl oxides (18-21) have been synthesized starting from 4-nitrophenol and 4-acetaminophenol respectively.All the compounds have been evaluated for their anthelmintic activity against Ancylostoma ceylanicum in hamsters, Nippostrongylus brasiliensis and Hymenolepsis nana in rats and Syphacia obvelata in mice.The results show that compounds 18, 19 and 33 remove 100percent of A. ceylanicum and H. nana at a single oral dose of 12.5-250 mg/kg.Compound 18 is also effective against N. brasiliensis in rats and S. obvelata in mice.