307313-77-5

Basic information

• Product Name: hexahydro-3-phenyl-6,7,8-trihydroxy-3R-[3α,5β,6β,7α,8β,8aβ]-5H-oxazolo[3,2-α]pyridine-5-carbonitrile
• Synonyms: hexahydro-3-phenyl-6,7,8-trihydroxy-3R-[3α,5β,6β,7α,8β,8aβ]-5H-oxazolo[3,2-α]pyridine-5-carbonitrile
• CAS NO: 307313-77-5
• Molecular Weight: 276.292
• Mol File: 307313-77-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: hexahydro-3-phenyl-6,7,8-trihydroxy-3R-[3α,5β,6β,7α,8β,8aβ]-5H-oxazolo[3,2-α]pyridine-5-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: hexahydro-3-phenyl-6,7,8-trihydroxy-3R-[3α,5β,6β,7α,8β,8aβ]-5H-oxazolo[3,2-α]pyridine-5-carbonitrile(307313-77-5)
• EPA Substance Registry System: hexahydro-3-phenyl-6,7,8-trihydroxy-3R-[3α,5β,6β,7α,8β,8aβ]-5H-oxazolo[3,2-α]pyridine-5-carbonitrile(307313-77-5)

Safety Data

• Hazardous Substances Data: 307313-77-5(Hazardous Substances Data)

Upstream product

• 19192-62-2 xylo-pentodialdose 
• 56613-80-0 D-2-phenylglycinol 
• 151-50-8 potassium cyanide 

Downstream Products

• 883882-47-1 (2R)-2-phenyl-2-[(1R,2S,3R,4R,5S)-2,3,4-trisbenzyloxy-7-phenyl-6,8-diazabicyclo[3.2.1]oct-6-en-8-yl]ethanol 
• 883882-48-2 (2R)-2-phenyl-2-[(1R,2S,3R,4R,5S)-2,3,4-trisbenzyloxy-7-butyl-6,8-diazabicyclo[3.2.1]oct-6-en-8-yl]ethanol 
• 883882-51-7 (2R)-2-phenyl-[(1R,2S,3R,5R,5S)-2,3,4-trisbenzyloxy-7-furan-6,8-diaazabicyclo[3.2.1]oct-6-en-8-yl]ethanol 

Relevant articles and documents

Synthesis of polyhydroxylated piperidines and evaluation as glycosidase inhibitors

A series of 16 new chiral nonracemic polyhydroxylated piperidines was synthesized utilizing several chiral β-amino-alcohols. They act as a nitrogen source, chirality inducer and iminium stabilizer, in the desymmetrization of meso-trihydroxylated glutaraldehyde. The biological activity of these compounds towards several glycosidases (α-d-glucosidase, α-d-mannosidase, α-l-fucosidase) has been evaluated.